健康研究
健康研究
건강연구
HEALTH RESEARCH
2014年
4期
391-394
,共4页
白蛋白%压疮%危险因素%Meta分析
白蛋白%壓瘡%危險因素%Meta分析
백단백%압창%위험인소%Meta분석
albumin%pressure ulcer%risk factor%meta-analysis
目的:明确血清白蛋白水平与压疮发生的相关性,为压疮风险评估指标的选择提供证据支持。方法计算机检索Cochrane library, EmBase, Pubmed, CBM, CNKI, VIP和WanFang数据库。根据纳入和排除标准对检索出的文献进行筛选、确定纳入文献。采用Revman4.2软件对数据进行统计分析。结果共纳入13个研究,包括患者2142人。 Meta分析结果显示压疮组白蛋白水平与非压疮组比较差异有统计学意义( WMD:-0.35,95%CI:-0.49,-0.20)。亚组分析发现研究对象不同可能为异质性来源。敏感性分析表明结果稳定性较好,漏斗图和失安全系数计算均提示发表偏倚的影响较小。结论血清白蛋白水平与压疮发生相关,建议以血清白蛋白水平替代食欲等主观营养评价条目,提高压疮评估量表的预测能力。
目的:明確血清白蛋白水平與壓瘡髮生的相關性,為壓瘡風險評估指標的選擇提供證據支持。方法計算機檢索Cochrane library, EmBase, Pubmed, CBM, CNKI, VIP和WanFang數據庫。根據納入和排除標準對檢索齣的文獻進行篩選、確定納入文獻。採用Revman4.2軟件對數據進行統計分析。結果共納入13箇研究,包括患者2142人。 Meta分析結果顯示壓瘡組白蛋白水平與非壓瘡組比較差異有統計學意義( WMD:-0.35,95%CI:-0.49,-0.20)。亞組分析髮現研究對象不同可能為異質性來源。敏感性分析錶明結果穩定性較好,漏鬥圖和失安全繫數計算均提示髮錶偏倚的影響較小。結論血清白蛋白水平與壓瘡髮生相關,建議以血清白蛋白水平替代食欲等主觀營養評價條目,提高壓瘡評估量錶的預測能力。
목적:명학혈청백단백수평여압창발생적상관성,위압창풍험평고지표적선택제공증거지지。방법계산궤검색Cochrane library, EmBase, Pubmed, CBM, CNKI, VIP화WanFang수거고。근거납입화배제표준대검색출적문헌진행사선、학정납입문헌。채용Revman4.2연건대수거진행통계분석。결과공납입13개연구,포괄환자2142인。 Meta분석결과현시압창조백단백수평여비압창조비교차이유통계학의의( WMD:-0.35,95%CI:-0.49,-0.20)。아조분석발현연구대상불동가능위이질성래원。민감성분석표명결과은정성교호,루두도화실안전계수계산균제시발표편의적영향교소。결론혈청백단백수평여압창발생상관,건의이혈청백단백수평체대식욕등주관영양평개조목,제고압창평고량표적예측능력。
Objective To find out the possible correlation between serum albumin and pressure ulcer and provide evidence for the selection of pressure ulcer risk assessment indicators .Method The Cochrane Library, Embase, Pubmed, CMB, CNKI, VIP and WanFang were searched for relevant previous studies .The included studies were confirmed according to the inclusion and exclusion criteria .The Rev man 4.2 was used for data analysis .Finding Thirteen studies ( included 2142 patients) met the inclusion criteria .Meta analysis results showed albumin in patients with and without pressure ulcers were significantly different(WMD:-0.35, 95%CI:-0.49,-0.20).Subgroup analysis indicated that the research object might be the sources of heterogeneity .Sensitivity analysis showed that the results were stable .Funnel flot and Fail-safe number showed that the publication bias was small .Conclusion Serum albumin is correlated to pressure ulcer .We suggest that serum albumin instead of appetite and other nutrition should be used as the evaluation indicators for pressure ulcer prediction .