传染病信息
傳染病信息
전염병신식
INFECTIOUS DISEASE INFORMATION
2014年
4期
193-197
,共5页
丙型肝炎,慢性%干扰素类%酶抑制剂
丙型肝炎,慢性%榦擾素類%酶抑製劑
병형간염,만성%간우소류%매억제제
hepatitis C,chronic%interferons%enzyme inhibitors
近年来，随着直接抗病毒药物（direct-acting antiviral drugs, DAAs）第一代NS3/4A蛋白酶抑制剂的上市，源源不断DAAs新药临床研究结果的公布及DAAs新药的陆续上市，为丙型肝炎的治疗带来了革命性的变化，一个DAAs时代已经来到。WHO首次发布了丙型肝炎防治指南，美国及欧洲肝病学会在线也及时更新了慢性丙型肝炎治疗的推荐意见。本文对慢性丙型肝炎的治疗进展及展望进行简述。
近年來，隨著直接抗病毒藥物（direct-acting antiviral drugs, DAAs）第一代NS3/4A蛋白酶抑製劑的上市，源源不斷DAAs新藥臨床研究結果的公佈及DAAs新藥的陸續上市，為丙型肝炎的治療帶來瞭革命性的變化，一箇DAAs時代已經來到。WHO首次髮佈瞭丙型肝炎防治指南，美國及歐洲肝病學會在線也及時更新瞭慢性丙型肝炎治療的推薦意見。本文對慢性丙型肝炎的治療進展及展望進行簡述。
근년래，수착직접항병독약물（direct-acting antiviral drugs, DAAs）제일대NS3/4A단백매억제제적상시，원원불단DAAs신약림상연구결과적공포급DAAs신약적륙속상시，위병형간염적치료대래료혁명성적변화，일개DAAs시대이경래도。WHO수차발포료병형간염방치지남，미국급구주간병학회재선야급시경신료만성병형간염치료적추천의견。본문대만성병형간염적치료진전급전망진행간술。
In recent years, with the approval of direct-acting antiviral agents (DAAs) against the NS3/4A serine protease for use, the publishing of the results of clinical research on novel DAAs, and the approval of novel DAAs for use, a dramatical change in treatment of hepatitis C has taken place, and a new era of hepatitis C therapy with DAAs has begun. World Health Organization issued its first global hepatitis C treatment guidelines. American Association for the Study of Liver Diseases and European Associa-tion for the Study of the Liver issued updated recommendations on treatment of hepatitis C online in time. This review focuses on the recent advances and future prospects in treatment of chronic hepatitis C.
