CAJ | 학술논문

发现于1976年的埃博拉出血热具有高传染性、高致病性和高病死率的特点，曾多次在非洲中西部暴发流行，病死率高达50%～90%。然而目前仍然未研制出有效的疫苗和抗病毒药物。始于2014年初的非洲西部暴发疫情是该病历史上最严重的疫情，感染和死亡人数已经超过了该病发现以来的总和，WHO宣布本次疫情为“国际关注的突发公共卫生事件”。国际公共卫生和医疗部门正在通力合作抗击这一烈性传染病。本文就该病研究现状及本次疫情暴发以来的一些特点进行回顾。
발현우1976년적애박랍출혈열구유고전염성、고치병성화고병사솔적특점，증다차재비주중서부폭발류행，병사솔고체50%～90%。연이목전잉연미연제출유효적역묘화항병독약물。시우2014년초적비주서부폭발역정시해병역사상최엄중적역정，감염화사망인수이경초과료해병발현이래적총화，WHO선포본차역정위“국제관주적돌발공공위생사건”。국제공공위생화의료부문정재통력합작항격저일렬성전염병。본문취해병연구현상급본차역정폭발이래적일사특점진행회고。
Ebola virus disease (EVD) is a severe, often fatal illness in humans, with high infectivity, high pathogenicity and high mortality rate. It first appeared in 1976, and several outbreaks of EVD have occurred in Western and Central Africa, with a case fatality rate of 50%-90%. However, no licensed vaccine and antiviral agent for EVD are available for use. The outbreak occur-ring in Western Africa in 2014 is the most severe outbreak of EVD in history, and the number of the infected and dead cases is lar-ger than the total number of those cases in the previous outbreaks of EVD. WHO declared the 2014 Ebola outbreak to be an inter-national public health emergency, and currently, international public health and medical settings are making common efforts to com-bat this virulent disease. The authors of this article summarize the research advances in EVD and the features of the 2014 Ebola out-break.