承德医学院学报
承德醫學院學報
승덕의학원학보
JOURNAL OF CHENGDE MEDICAL
2014年
4期
290-292
,共3页
徐杨璐%赵胜男%刘素丽%李守拙
徐楊璐%趙勝男%劉素麗%李守拙
서양로%조성남%류소려%리수졸
黄芩%加速试验法%红外光谱法%高效液相色谱法
黃芩%加速試驗法%紅外光譜法%高效液相色譜法
황금%가속시험법%홍외광보법%고효액상색보법
Scutellaria baicalensis Georgi%Accelerated test%Infrared spectroscopy (IR)%High performance liquid chromatography (HPLC)
目的:采用加速试验法研究黄芩药材的贮藏稳定性。方法:黄芩药材置于湿度为70%、温度为37℃的恒温箱内,分别于0、1、2、个月取样,以红外光谱法和高效液相色谱法分析黄芩药材的整体变化和局部变化。结果:加速试验条件下,红外光谱法显示在贮藏期内黄芩中有效成分黄酮类已酸变为其它成分,糖(苷)类物质的含量减少;高效液相色谱法显示,在贮藏期内黄芩苷和汉黄芩苷的含量明显下降,黄芩素和汉黄芩素的含量先增加后减少。结论:黄芩药材的质量在贮藏期内发生明显变化,提示应有效控制黄芩药材的贮藏期。
目的:採用加速試驗法研究黃芩藥材的貯藏穩定性。方法:黃芩藥材置于濕度為70%、溫度為37℃的恆溫箱內,分彆于0、1、2、箇月取樣,以紅外光譜法和高效液相色譜法分析黃芩藥材的整體變化和跼部變化。結果:加速試驗條件下,紅外光譜法顯示在貯藏期內黃芩中有效成分黃酮類已痠變為其它成分,糖(苷)類物質的含量減少;高效液相色譜法顯示,在貯藏期內黃芩苷和漢黃芩苷的含量明顯下降,黃芩素和漢黃芩素的含量先增加後減少。結論:黃芩藥材的質量在貯藏期內髮生明顯變化,提示應有效控製黃芩藥材的貯藏期。
목적:채용가속시험법연구황금약재적저장은정성。방법:황금약재치우습도위70%、온도위37℃적항온상내,분별우0、1、2、개월취양,이홍외광보법화고효액상색보법분석황금약재적정체변화화국부변화。결과:가속시험조건하,홍외광보법현시재저장기내황금중유효성분황동류이산변위기타성분,당(감)류물질적함량감소;고효액상색보법현시,재저장기내황금감화한황금감적함량명현하강,황금소화한황금소적함량선증가후감소。결론:황금약재적질량재저장기내발생명현변화,제시응유효공제황금약재적저장기。
Objective:Tostudythestoragestability ofScutellaria baicalensis Georgi by accelerated test. Methods:The Scutellaria baicalensis Georgi was stored in incubator chamber with humidity was 70%, and temperature was 37℃. Infrared spectroscopy (IR) and high performance liquid chromatography (HPLC) were used to analyze the general changes and local changes of Scutellaria baicalensis Georgi respectively 0, 1, 2, and 3 months after storage. Results:IR results showed, during storage,theeffectivecomponentsofScutellariabaicalensisGeorgi-Flavonoidcompoundacidized into othercomponentsand the content of glycoside Substances reduced. HPLC results showed, during storage, the content of baicalin and wogonoside reduced obviously, while the content of baicalein and wogonin increased first and then decreased. Conclusions: The quality of Scutellaria baicalensis Georgi changed significantly during storage, so should control the storage period of Scutellaria baicalensisGeorgieffectively.