CAJ | 학술논문

目的：分析使用奥曲肽治疗急性胰腺炎（AP）的临床效果及其应用价值。方法：选取2011年5月～2013年8月收治的AP患者114例，随机分为观察组与对照组各57例，对照组实施禁食、抑酸、胃肠减压等传统常规治疗，观察组在此基础上使用奥曲肽进行治疗，对比观察两组患者临床疗效。结果：观察组治疗总有效率明显高于对照组，相比对照组，观察组胃动素水平明显升高而胃泌素水平则明显下降，血尿淀粉酶恢复、首次通便、症状缓解、胃肠减压及住院时间均明显缩短（P＜0.05）。结论：使用奥曲肽治疗AP能够有效提高临床疗效，改善胃动素、胃泌素分泌，缩短症状缓解与机体恢复时间。
목적：분석사용오곡태치료급성이선염（AP）적림상효과급기응용개치。방법：선취2011년5월～2013년8월수치적AP환자114례，수궤분위관찰조여대조조각57례，대조조실시금식、억산、위장감압등전통상규치료，관찰조재차기출상사용오곡태진행치료，대비관찰량조환자림상료효。결과：관찰조치료총유효솔명현고우대조조，상비대조조，관찰조위동소수평명현승고이위비소수평칙명현하강，혈뇨정분매회복、수차통편、증상완해、위장감압급주원시간균명현축단（P＜0.05）。결론：사용오곡태치료AP능구유효제고림상료효，개선위동소、위비소분비，축단증상완해여궤체회복시간。
To observe the clinical effects and to evaluate octreotide in treating acute pancreatitis.Methods:From May 2011 to August 2013, 114 patients with acute pancreatitis were randomly divided into observation group and control group, each group contains 57 patients respectively. The patients in the control group were assigned to routine treatment including fasting, acid suppression and gastrointestinal decompression. The patients in the observation group were given octreotide combined with route treatment. The clinical effects of the two groups were compared.Results:The total effective rate of the observation group was significantly higher than that of the control group, and the motilin level was significantly elevated while the gastrin level was significantly decreased in the observation group compared to the control group. Additionally, urine amylase level recovery, first catharsis, symptoms remission, gastrointestinal pressure decrease and length of stay were significantly shorter(P<0.05).Conclusion:The application of octreotide treatment of acute pancreatitis can effectively improve the clinical efficacy and improve motilin and gastrin secretion, relieve symptoms and shorten the recovery time of the body.