中国医学前沿杂志(电子版)
中國醫學前沿雜誌(電子版)
중국의학전연잡지(전자판)
CHINESE JOURNAL OF THE FRONTIERS OF MEDICAL SCIENCE(ELECTRONIC VERSION)
2014年
8期
55-57
,共3页
子痫前期%抵抗素%瘦素
子癇前期%牴抗素%瘦素
자간전기%저항소%수소
Preeclampsia%Resistin%Leptin
目的:通过研究子痫前期孕妇及正常孕妇外周血中抵抗素与瘦素的含量及相关性,探讨其在子痫前期发病中的作用,评价其诊断价值。方法选择20例子痫前期孕妇为病例组,另选20例正常孕妇为对照组,采用酶联免疫吸附试验(ELISA)检测孕妇外周血中抵抗素及瘦素水平,ROC曲线分析其与子痫前期发病的相关性。结果①病例组孕妇血清瘦素值较对照组明显升高(P<0.05);②血清瘦素、抵抗素水平与子痫前期发病密切相关。结论血清抵抗素、瘦素水平升高与子痫前期发病有关。抵抗素>22.25μg/L时,灵敏度为80%,特异度为85%;瘦素>17.05μg/L时,灵敏度为80%,特异度为80%;二者联合监测能更好地预测子痫前期发病。
目的:通過研究子癇前期孕婦及正常孕婦外週血中牴抗素與瘦素的含量及相關性,探討其在子癇前期髮病中的作用,評價其診斷價值。方法選擇20例子癇前期孕婦為病例組,另選20例正常孕婦為對照組,採用酶聯免疫吸附試驗(ELISA)檢測孕婦外週血中牴抗素及瘦素水平,ROC麯線分析其與子癇前期髮病的相關性。結果①病例組孕婦血清瘦素值較對照組明顯升高(P<0.05);②血清瘦素、牴抗素水平與子癇前期髮病密切相關。結論血清牴抗素、瘦素水平升高與子癇前期髮病有關。牴抗素>22.25μg/L時,靈敏度為80%,特異度為85%;瘦素>17.05μg/L時,靈敏度為80%,特異度為80%;二者聯閤鑑測能更好地預測子癇前期髮病。
목적:통과연구자간전기잉부급정상잉부외주혈중저항소여수소적함량급상관성,탐토기재자간전기발병중적작용,평개기진단개치。방법선택20례자간전기잉부위병례조,령선20례정상잉부위대조조,채용매련면역흡부시험(ELISA)검측잉부외주혈중저항소급수소수평,ROC곡선분석기여자간전기발병적상관성。결과①병례조잉부혈청수소치교대조조명현승고(P<0.05);②혈청수소、저항소수평여자간전기발병밀절상관。결론혈청저항소、수소수평승고여자간전기발병유관。저항소>22.25μg/L시,령민도위80%,특이도위85%;수소>17.05μg/L시,령민도위80%,특이도위80%;이자연합감측능경호지예측자간전기발병。
Objective To assess serum resistin and leptin levels as a marker for preeclampsia (PE) and to explore the possibility of AECA and leptin being a marker of severity of preeclampsia. Method Comparative prospective study was conducted among two groups (control and study group) according to the absence or presence of clinical parameters of preeclampsia. Serum resistin and Leptin was determined using ELISA method. Result Serum resistin and leptin was signiifcantly higher in preeclampsia (P<0.05). Conclusion Resistin and leptin levels were found to be signiifcantly higher among all preeclampsia patients when compared to the control group;serum resistin and leptin in preeclampsia in the correlation suggesting that mechanisms between them, ROC curve analysis has shown that a cut off value serum resistin>22.25μg/L and serum leptin>17.05μg/L can be used to detect presence of preeclampsia.