中国药物警戒
中國藥物警戒
중국약물경계
CHINESE JOURNAL OF PHARMACOVIGILANCE
2014年
8期
462-464
,共3页
陈澈%院立新%李净娅%张根明
陳澈%院立新%李淨婭%張根明
진철%원립신%리정아%장근명
脑出血%活血化瘀%生活质量%临床观察
腦齣血%活血化瘀%生活質量%臨床觀察
뇌출혈%활혈화어%생활질량%림상관찰
intracerebralhemorrhage%blood-activatingandstasis-removingmethod%livingquality%clinicalobservation
目的:观察活血化瘀方案对脑出血患者生活质量改善的影响。方法228例脑出血患者随机分为两组。对照组114例予内科基础治疗,试验组114例在此基础上予醒脑静注射液静脉滴注14天,辨证服用活血化瘀免煎颗粒21天,21天后口服脑血疏口服液至发病3个月。观察两组基于中风患者报告的临床结局(PRO量表)评分变化情况。结果试验组在入组第21天及3个月时PRO量表的生理功能、心理精神状态、社会关系和治疗满意度等指标总分均低于对照组(P<0.05)。且各单项指标分值在一些时点亦低于对照组(P<0.05)。结论活血化瘀方案可改善脑出血患者在发病后一定时期内的生活质量,对于提高脑出血的临床疗效有一定意义。
目的:觀察活血化瘀方案對腦齣血患者生活質量改善的影響。方法228例腦齣血患者隨機分為兩組。對照組114例予內科基礎治療,試驗組114例在此基礎上予醒腦靜註射液靜脈滴註14天,辨證服用活血化瘀免煎顆粒21天,21天後口服腦血疏口服液至髮病3箇月。觀察兩組基于中風患者報告的臨床結跼(PRO量錶)評分變化情況。結果試驗組在入組第21天及3箇月時PRO量錶的生理功能、心理精神狀態、社會關繫和治療滿意度等指標總分均低于對照組(P<0.05)。且各單項指標分值在一些時點亦低于對照組(P<0.05)。結論活血化瘀方案可改善腦齣血患者在髮病後一定時期內的生活質量,對于提高腦齣血的臨床療效有一定意義。
목적:관찰활혈화어방안대뇌출혈환자생활질량개선적영향。방법228례뇌출혈환자수궤분위량조。대조조114례여내과기출치료,시험조114례재차기출상여성뇌정주사액정맥적주14천,변증복용활혈화어면전과립21천,21천후구복뇌혈소구복액지발병3개월。관찰량조기우중풍환자보고적림상결국(PRO량표)평분변화정황。결과시험조재입조제21천급3개월시PRO량표적생리공능、심리정신상태、사회관계화치료만의도등지표총분균저우대조조(P<0.05)。차각단항지표분치재일사시점역저우대조조(P<0.05)。결론활혈화어방안가개선뇌출혈환자재발병후일정시기내적생활질량,대우제고뇌출혈적림상료효유일정의의。
ObjectiveToobservetheeffectforimprovinglivingqualityofintracerebralhemorrhagewithblood-activating and stasis-removing therapy. Methods A total of 228 cases with cerebral hemorrhage were randomly divided into the treatment group (n=114) and the control group (n=114). The control group was treated with the basic treatment of internal medicine. On the basis of it, the treatment group received intravenous infusion with Xingnaojing injection for 2 weeks and was given TCM granules for 21 days dynamically and dialectically. After these, the treatment group was asked to drink Naoxueshu oral liquid until the 3rd month of incidence. The clinical outcome assessment of pa-tient reported outcomes (PRO) scores were observed in two groups. Results Compared with the first day, the treat-ment group PRO scores were superior to control group in 21th day and 3rd month after entering the group (P<0.05). And the single index in some time was also lower than the control group (P<0.05). Conclusion Intracere-bral hemorrhage with blood-activating and stasis-removing therapy had an effective result in improving living quali-ty in a certain period of time. It is good to improve the clinical efficacy.