CAJ | 학술논문

目的：探究社区老年人弗明汉评分与认知功能的相关性。 　　方法：利用弗明汉评分方程评价276名健康老年人发生冠心病的风险值。根据弗明汉评分值将研究对象分为高危组（10年内发生冠心病风险＞20%），中危组（10年内发生冠心病风险10%~20%），低危组（10年内发生冠心病风险＜10%）。用简易精神状态量表（MMSE）与中国成人智力量表（CISA）评估认知能力，比较不同危险分组间的认知功能水平差异。 　　结果：随着发生冠心病的风险的递增（即低危组、中危组、高危组），研究对象的MMSE得分下降[（26.9±1.45）分vs（24.3±1.53）分vs（22.2±1.43）分，P=0.014]；Pearson相关分析的结果显示，研究对象的MMSE得分与弗明汉评分值呈负相关关系（r=-0.213，P<0.001），弗明汉评分得分对研究对象认知功能有显著相关关系的项目包括：MMSE得分、问题解答、宫格补缺、口头运算、词义分辨、分类概括（r=-0.247，-0.167，-0.132，-0.152，-0.256，P均<0.05）。 　　结论：健康老年人发生冠心病的风险水平与认知功能存在负相关，弗明汉评分危险积分值越高，认知水平越低。
목적：탐구사구노년인불명한평분여인지공능적상관성。 　　방법：이용불명한평분방정평개276명건강노년인발생관심병적풍험치。근거불명한평분치장연구대상분위고위조（10년내발생관심병풍험＞20%），중위조（10년내발생관심병풍험10%~20%），저위조（10년내발생관심병풍험＜10%）。용간역정신상태량표（MMSE）여중국성인지역량표（CISA）평고인지능력，비교불동위험분조간적인지공능수평차이。 　　결과：수착발생관심병적풍험적체증（즉저위조、중위조、고위조），연구대상적MMSE득분하강[（26.9±1.45）분vs（24.3±1.53）분vs（22.2±1.43）분，P=0.014]；Pearson상관분석적결과현시，연구대상적MMSE득분여불명한평분치정부상관관계（r=-0.213，P<0.001），불명한평분득분대연구대상인지공능유현저상관관계적항목포괄：MMSE득분、문제해답、궁격보결、구두운산、사의분변、분류개괄（r=-0.247，-0.167，-0.132，-0.152，-0.256，P균<0.05）。 　　결론：건강노년인발생관심병적풍험수평여인지공능존재부상관，불명한평분위험적분치월고，인지수평월저。
Objective: To study the relationship between Framingham risk score for coronary artery disease (CAD) and cognitive function in healthy community elders. Methods: A total of 276 healthy community elders were evaluated by Framingham score to predict the risk for suffering from CAD in 10 years. The subjects were divided into 3 groups. High risk group (the risk > 20%), n=46, Mid risk group (the risk at 10%-20%), n=76 and Low risk group (the risk < 10%), n=154. The cognitive function was measured by mini-mental state examination (MMSE) and China adult intelligence scale (CISA). The differences of cognitive function levels to 3 CAD risk groups were studied. Results: With the increased CAD incidence from Low risk, Mid risk to High risk groups, the MMSE score reduced accordingly (26.9 ± 1.45) vs (24.3 ± 1.53) vs (22.2 ± 1.43), P=0.014. Pearson analysis presented that MMSE score was negatively related to Framingham risk score (r=-0.213, P<0.001). There were several elements of cognitive function related to Framingham risk score including MMSE score, question answering, grid filling, oral arithmetic and word distinguishing (r=-0.247), (r=-0.167), (r=-0.132), (r=-0.152) and (r-0.256), all P<0.05. Conclusion: CAD risk level was negatively related to cognitive function, the higher Framingham risk score resulted in the lower cognitive function in healthy community elder subjects.