CAJ | 학술논문

目的：临床上肠外营养（parenteral nutrition， PN）支持仍存在一定的不规范性。文中通过分析PN的临床应用情况，为临床合理用药提供依据。方法采用加权随机法抽取南京军区南京总医院2012年4月至2013年3月每个月所有病区5％的住院患者信息，使用NRS-2002营养风险筛查评分简表评估患者是否需要营养支持，并对PN支持的科室分布、PN具体构成及全合一营养非蛋白热卡与氮比值分布区间进行统计和分析。结果有393例患者接受PN支持，NRS-2002营养风险筛查评分简表评分＜3分的患者有217例，而≥3分的患者有176例，两者差异无统计学意义（ P＞0．05）。有18个科室使用PN，普通外科使用“全合一”营养支持方式最高。133例使用全合一营养支持的患者中有37例患者（27．82％）使用天数＜7 d。全合一营养的非蛋白热卡与氮比值为100∶1～150∶1的仅占28．57％。结论 PN已在临床科室广泛使用，但处方的合理性仍有待加强。药师应从药学角度协助医生制订合理的给药方案。
목적：림상상장외영양（parenteral nutrition， PN）지지잉존재일정적불규범성。문중통과분석PN적림상응용정황，위림상합리용약제공의거。방법채용가권수궤법추취남경군구남경총의원2012년4월지2013년3월매개월소유병구5％적주원환자신식，사용NRS-2002영양풍험사사평분간표평고환자시부수요영양지지，병대PN지지적과실분포、PN구체구성급전합일영양비단백열잡여담비치분포구간진행통계화분석。결과유393례환자접수PN지지，NRS-2002영양풍험사사평분간표평분＜3분적환자유217례，이≥3분적환자유176례，량자차이무통계학의의（ P＞0．05）。유18개과실사용PN，보통외과사용“전합일”영양지지방식최고。133례사용전합일영양지지적환자중유37례환자（27．82％）사용천수＜7 d。전합일영양적비단백열잡여담비치위100∶1～150∶1적부점28．57％。결론 PN이재림상과실엄범사용，단처방적합이성잉유대가강。약사응종약학각도협조의생제정합리적급약방안。
Objective Clinical parenteral nutrition( PN) support still lacks in standards on some degree .This paper was to analyze the clinical application of PN support in our hospital in order to provide the basis for clinical rational drug use . Methods Random weighting method was applied to collect 5% hospitalized patients′information from each patient unit each month from April 2012 to March 2013 in Nanjing Gerneral Hospital of Nanjing Military Region .NRS-2002 nutrition risk screening was applied to eval-uate whether the patient needed PN support .Statistical analysis were carried out on patients supported with parenteral nutrition from department distribution, PN detailed components and distribution intervals of aII in one admixture non-protein calorie and nitrogen ra-tio. Results According to the survey, 393 patients had received PN support, including 217 cases′NRS score <3 and 176 cases′NRS score ≥3.General surgery department ranked the first in the cases of using"all in one"admixture support.Among 133 cases receiving all in one admixture support, the course of 37 cases(27.82%) <7 d.The aII in one admixture non-protein calorie and ni-trogen ratio(100~150∶1) only took up 28.57%. Conclusion Although PN has got wide application in clinical departments, the rationality of prescription should be strengthened .Pharmacists should help doctors set up appropriate prescription from the aspect of pharmacy.