CAJ | 학술논문

沙门菌是引起人类食物中毒最常见的致病菌。在畜牧养殖业中大量和广泛使用抗生素，造成猪源沙门菌耐药性日益增加，甚至出现多重耐药现象。美国很早就开展了猪源沙门菌耐药性监测工作，我国也对猪源沙门菌耐药性检测越来越重视。论文概述了猪源沙门菌对常用抗菌药物（β-内酰胺类、喹诺酮类、氨基糖苷类、四环素类以及氯霉素和磺胺类等）的耐药机制。在此基础上，阐述了中、美两国部分地区近10年猪源沙门菌的耐药性调查。以期对猪源沙门菌的耐药机制及耐药性程度深入认识，为养猪业生产中猪源沙门菌的防控和耐药监测提供参考。
사문균시인기인류식물중독최상견적치병균。재축목양식업중대량화엄범사용항생소，조성저원사문균내약성일익증가，심지출현다중내약현상。미국흔조취개전료저원사문균내약성감측공작，아국야대저원사문균내약성검측월래월중시。논문개술료저원사문균대상용항균약물（β-내선알류、규낙동류、안기당감류、사배소류이급록매소화광알류등）적내약궤제。재차기출상，천술료중、미량국부분지구근10년저원사문균적내약성조사。이기대저원사문균적내약궤제급내약성정도심입인식，위양저업생산중저원사문균적방공화내약감측제공삼고。
Salmonella is a common kind of pathogenic bacteria which cause food poisoning to human .Since antimicrobial agents have been widely used ,the drug resistance of Salmonella is getting more and more strengthened ,even emerges the multi-drug resistance .The United States established their own national monitoring system early ,and our country has paid more attention to this .This paper made a general re-view on mechanisms of antimicrobial (including β-lactams , quinolones , aminoglycosides , tetracyclines , chloramphenicol and sulfa ) resistance of Salmonella between China and America for nearly a decade , which aimed to provide some reference resources for control and surveillance of drug resistance of swine Salmonella.