中国急救医学
中國急救醫學
중국급구의학
CHINESE JOURNAL OF CRITICAL CARE MEDICINE
2014年
9期
833-836
,共4页
新生儿呼吸窘迫综合征(NRDS)%同步间歇正压通气(SIPPV)%容量控制通气%辅助/控制通气(A/C)%疗效
新生兒呼吸窘迫綜閤徵(NRDS)%同步間歇正壓通氣(SIPPV)%容量控製通氣%輔助/控製通氣(A/C)%療效
신생인호흡군박종합정(NRDS)%동보간헐정압통기(SIPPV)%용량공제통기%보조/공제통기(A/C)%료효
Neonatal respiratory distress syndrome%Synchronized intermittent positive pressure ventilation%Volume controlled ventilation%Assist/control ventilation%Efficacy
目的：比较同步间歇正压联合容量控制通气（ SIPPV＋VG）与传统的辅助/控制（A/C）通气对治疗新生儿呼吸窘迫综合征（NRDS）的疗效和并发症情况。方法66例NRDS患儿随机分为SIPPV＋VG组和A/C组，每组33例，比较两组患儿不同时间的氧合状况以及并发症情况。结果两组患儿动脉血氧分压/吸入氧体积分数（ P/F）和肺泡-动脉血氧分压比（ a/APO2）均随时间推移而显著增加（F＝31．25、16.82，P＜0．05），SIPPV＋VG组P/F和a/APO2均显著高于A/C组（F＝9．54、6．73，P＜0．05），SIPPV＋VG组的氧疗时间和呼吸机使用时间均显著少于A/C组，SIPPV＋VG组出现呼吸机相关性肺炎（ VAP）和气漏的比例显著低于A/C组。结论SIPPV＋VG通气模式并发症低，安全有效，值得临床推广。
目的：比較同步間歇正壓聯閤容量控製通氣（ SIPPV＋VG）與傳統的輔助/控製（A/C）通氣對治療新生兒呼吸窘迫綜閤徵（NRDS）的療效和併髮癥情況。方法66例NRDS患兒隨機分為SIPPV＋VG組和A/C組，每組33例，比較兩組患兒不同時間的氧閤狀況以及併髮癥情況。結果兩組患兒動脈血氧分壓/吸入氧體積分數（ P/F）和肺泡-動脈血氧分壓比（ a/APO2）均隨時間推移而顯著增加（F＝31．25、16.82，P＜0．05），SIPPV＋VG組P/F和a/APO2均顯著高于A/C組（F＝9．54、6．73，P＜0．05），SIPPV＋VG組的氧療時間和呼吸機使用時間均顯著少于A/C組，SIPPV＋VG組齣現呼吸機相關性肺炎（ VAP）和氣漏的比例顯著低于A/C組。結論SIPPV＋VG通氣模式併髮癥低，安全有效，值得臨床推廣。
목적：비교동보간헐정압연합용량공제통기（ SIPPV＋VG）여전통적보조/공제（A/C）통기대치료신생인호흡군박종합정（NRDS）적료효화병발증정황。방법66례NRDS환인수궤분위SIPPV＋VG조화A/C조，매조33례，비교량조환인불동시간적양합상황이급병발증정황。결과량조환인동맥혈양분압/흡입양체적분수（ P/F）화폐포-동맥혈양분압비（ a/APO2）균수시간추이이현저증가（F＝31．25、16.82，P＜0．05），SIPPV＋VG조P/F화a/APO2균현저고우A/C조（F＝9．54、6．73，P＜0．05），SIPPV＋VG조적양료시간화호흡궤사용시간균현저소우A/C조，SIPPV＋VG조출현호흡궤상관성폐염（ VAP）화기루적비례현저저우A/C조。결론SIPPV＋VG통기모식병발증저，안전유효，치득림상추엄。
Objective To compare the efficacy and complications between synchronized intermittent positive pressure ventilation combined volume controlled ventilation ( SIPPV+VG) with the traditional assist/control ( A/C ) ventilation in the treatment of neonatal respiratory distress syndrome ( NRDS) and guide the clinical application .Methods Sixty -six cases of NRDS were randomly divided into SIPPV+VG group and A/C group, 33 cases in each group.SIPPV+VG group received synchronized intermittent positive pressure ventilation combined volume controlled ventilation , A/C group received assist /control ventilation .Oxygenation status and complications were compared between two groups.Results P/F and a/APO2 were significantly increased with time in both group (F=31.25, 16.82, P<0.05), while P/F and a/APO2 in SIPPV+VG group were significantly higher than those in A/C group(F=9.54、 6.73, P <0.05).Duration of oxygen therapy and mechanical ventilation in SIPPV+VG group was significantly less than that in A/C group.The incidence of ventilator associated pneumonia ( VAP) and gas leakage in SIPPV +VG group were significantly less than those in A/C group.Conclusion SIPPV +VG ventilation has advantages in safety and efficacy , and is worthy of clinical application .
