CAJ | 학술논문

目的：观察飞秒激光和角膜板层刀制瓣 LASIK 术后泪膜的变化。 　　方法：回顾性分析150例300眼近视患者,根据制作角膜瓣方法不同分为两组,组1为飞秒激光( Intralase FS60KHz)制作角膜瓣,95例190眼；组2为 Moria M290号板层刀制瓣,55例110眼。观察两组术前、术后1wk；1,3,6mo 患者的干眼症状评分、泪膜破裂时间(tear break-up time,BUT)、泪液分泌试验(Schirmer I test,S I t)、角膜荧光素染色(corneal fluorescence staining,FL)评分的变化。 　　结果：干眼症状评分：两组术后1wk；1,3mo 差异有统计学意义(P<0.05),术后6mo 差异无统计学意义(P>0.05)。BUT：两组术后1wk；1,3mo 差异有统计学意义(P<0.05),术后6mo 差异无统计学意义(P>0.05)。 SchirmerⅠ试验：两组术后1wk；1,3mo 差异有统计学意义(P<0.05),术后6mo 差异无统计学意义(P>0.05)。荧光素染色评分：两组术后1wk；1,3mo 差异有统计学意义( P<0.05),术后6mo 差异无统计学意义(P>0.05)。 　　结论：飞秒激光和角膜板层刀制瓣 LASIK 术后早期泪膜功能减退,但飞秒激光制瓣术后泪膜功能恢复更快。
목적：관찰비초격광화각막판층도제판 LASIK 술후루막적변화。 　　방법：회고성분석150례300안근시환자,근거제작각막판방법불동분위량조,조1위비초격광( Intralase FS60KHz)제작각막판,95례190안；조2위 Moria M290호판층도제판,55례110안。관찰량조술전、술후1wk；1,3,6mo 환자적간안증상평분、루막파렬시간(tear break-up time,BUT)、루액분비시험(Schirmer I test,S I t)、각막형광소염색(corneal fluorescence staining,FL)평분적변화。 　　결과：간안증상평분：량조술후1wk；1,3mo 차이유통계학의의(P<0.05),술후6mo 차이무통계학의의(P>0.05)。BUT：량조술후1wk；1,3mo 차이유통계학의의(P<0.05),술후6mo 차이무통계학의의(P>0.05)。 SchirmerⅠ시험：량조술후1wk；1,3mo 차이유통계학의의(P<0.05),술후6mo 차이무통계학의의(P>0.05)。형광소염색평분：량조술후1wk；1,3mo 차이유통계학의의( P<0.05),술후6mo 차이무통계학의의(P>0.05)。 　　결론：비초격광화각막판층도제판 LASIK 술후조기루막공능감퇴,단비초격광제판술후루막공능회복경쾌。
To observe the changes of tear film on the patients after laser in situ keratomileusis(LASlK)with corneal flap created by femtosecond laser and microkeratome. ●METHODS: Totally 150 patients (300 eyes) with myopia received operation of LASlK. Patients were divided into two groups according to the methods of making corneal flap. The patients of group one were assigned to receiving LASlK with corneal flap creation by lntralase femtosecond laser (190 eyes of 95 patients), group two were assigned to receiving LASlK with corneal flap creation by microkeratome ( 110 eyes of 55 patients ). Dry eye symptom score, tear break-up time (BUT), Schirmer Ⅰtest(Slt), corneal fluorescein staining(FL)were recorded preoperatively and postoperatively at 1wk; 1, 3 and 6mo. ●RESULTS: Dry eye symptom score: there existed obvious differences at 1wk; 1, 3mo between two groups(P<0. 05). While no such obvious differences existed in the 6mo between two groups(P>0. 05). BUT: there existed obvious differences at 1wk, 1, 3mo between two groups(P<0. 05). While no such obvious differences existed at 6mo between two groups(P>0. 05). SchirmerⅠ test: there existed obvious differences in the 1wk, 1, 3mo between two groups(P<0. 05). Whileno such obvious differences existed in the 6mo between 2 groups(P>0. 05). FL: there existed obvious differences in the 1wk, 1, 3mo between two groups(P<0. 05). While no such obvious differences existed in the 6mo between two groups(P>0. 05). ●CONCLUSlON: The early stability of tear film decrease after operation in both of the two groups. The dry eye symptoms are lighter and recover faster.