国际眼科杂志
國際眼科雜誌
국제안과잡지
INTERNATIONAL JOURNAL OF OPHTHALMOLOGY
2014年
9期
1707-1709
,共3页
左氧氟沙星%角膜炎%结膜炎%耐药性
左氧氟沙星%角膜炎%結膜炎%耐藥性
좌양불사성%각막염%결막염%내약성
levofloxacin%keratitis%conjunctivitis%drug tolerance
目的：研究左氧氟沙星治疗重症细菌性角膜炎和结膜炎的疗效以及耐药性。<br> 方法：将我院收治的195例重症细菌性角膜炎和结膜炎患者作为观察对象，随机均分为 A 组、B 组和 C 组，分别给予左氧氟沙星、氧氟沙星和氯霉素进行治疗，统计治疗数据，评价不同治疗方法治疗的效果和耐药性。<br> 结果：采用左氧氟沙星治疗的 A 组患者痊愈54例(83.1%)，显效7例(10.8%)，有效3例(4.6%)，无效1例(1.5%)；采用氧氟沙星治疗的 B 组患者痊愈25例(38.5%)，显效6例(9.2%)，有效23例(35.4%)，无效11例(16.9%)；采用氯霉素治疗的 C 组患者痊愈4例(6.2%)，显效3例(4.6%)，有效36例(55.4%)，无效22例(33.8%)，组间治疗效果和耐药性存在显著差异(P <0.05)。<br> 结论：左氧氟沙星治疗重症细菌性结膜炎和角膜炎起效快，效果好，不易产生抗药性，值得推广借鉴。
目的：研究左氧氟沙星治療重癥細菌性角膜炎和結膜炎的療效以及耐藥性。<br> 方法：將我院收治的195例重癥細菌性角膜炎和結膜炎患者作為觀察對象，隨機均分為 A 組、B 組和 C 組，分彆給予左氧氟沙星、氧氟沙星和氯黴素進行治療，統計治療數據，評價不同治療方法治療的效果和耐藥性。<br> 結果：採用左氧氟沙星治療的 A 組患者痊愈54例(83.1%)，顯效7例(10.8%)，有效3例(4.6%)，無效1例(1.5%)；採用氧氟沙星治療的 B 組患者痊愈25例(38.5%)，顯效6例(9.2%)，有效23例(35.4%)，無效11例(16.9%)；採用氯黴素治療的 C 組患者痊愈4例(6.2%)，顯效3例(4.6%)，有效36例(55.4%)，無效22例(33.8%)，組間治療效果和耐藥性存在顯著差異(P <0.05)。<br> 結論：左氧氟沙星治療重癥細菌性結膜炎和角膜炎起效快，效果好，不易產生抗藥性，值得推廣藉鑒。
목적：연구좌양불사성치료중증세균성각막염화결막염적료효이급내약성。<br> 방법：장아원수치적195례중증세균성각막염화결막염환자작위관찰대상，수궤균분위 A 조、B 조화 C 조，분별급여좌양불사성、양불사성화록매소진행치료，통계치료수거，평개불동치료방법치료적효과화내약성。<br> 결과：채용좌양불사성치료적 A 조환자전유54례(83.1%)，현효7례(10.8%)，유효3례(4.6%)，무효1례(1.5%)；채용양불사성치료적 B 조환자전유25례(38.5%)，현효6례(9.2%)，유효23례(35.4%)，무효11례(16.9%)；채용록매소치료적 C 조환자전유4례(6.2%)，현효3례(4.6%)，유효36례(55.4%)，무효22례(33.8%)，조간치료효과화내약성존재현저차이(P <0.05)。<br> 결론：좌양불사성치료중증세균성결막염화각막염기효쾌，효과호，불역산생항약성，치득추엄차감。
To evaluate the curative effect and drug tolerance in the treatment of severe bacterial keratitis and conjunctivitis by levofloxacin. <br> ●METHODS: Totally 195 patients with severe bacterial keratitis and conjunctivitis were included in this study. Based on the sequence of enrollment, they were randomly divided into three groups: group A ( 65 patients) received levofloxacin, group B ( 65 patients) received suture method under microscope, group C received suture method with loupe besides the same basic operative treatment in the two groups. The curative effect and drug tolerance were observed and compared statistically. <br> ●RESULTS: ln group A, 54 cases were cured, in the rate of 83. 1%, 7 cases ( 10. 8%) were excellent, 3 cases (4. 6%) were valid, 1 case (1. 5%) was invalid. ln group B, 25 cases (38. 5%) were cured, 6 cases (9. 2%) were excellent, 23 cases (35. 4%) were valid, 11 cases (16. 9%) were invalid. ln group C, 4 cases (6. 2%) were cured, 3 cases (4. 6%) were excellent, 36 cases (55. 4%) were valid, 22 cases (33. 8%) were invalid. The curative effect and drug tolerance among groups had obvious differences (P<0. 05). <br> ●CONCLUSlON: Levofloxaoin is effective and safe for the treatment of bacterial conjunctivitis and keratitis, which is not resistant and worthy of promotion.
