CAJ | 학술논문

目的：总结抗结核药物所致的视神经炎临床特点，探讨防治对策。 　　方法：回顾性分析广州市胸科医院2003-01/2013-01门诊和病房患者在抗结核治疗过程中出现药物性视神经炎的临床特点。 　　结果：抗结核药物治疗引起的药物性视神经炎不多见(17/60000)，以球后视神经炎多见，引起视神经炎的抗结核药物主要是乙胺丁醇，其次是异烟肼、链霉素。明确诊断后及时停用与视神经炎相关的结核药，并根据病情给予补充维生素，扩张血管，激素等治疗，患者的视力都有不同程度的提高。 　　结论：在使用抗结核药期间要注意患者视力变化情况出现突发视力下降应作眼科检查，并及时给予干预，防止失明的严重后果。
목적：총결항결핵약물소치적시신경염림상특점，탐토방치대책。 　　방법：회고성분석엄주시흉과의원2003-01/2013-01문진화병방환자재항결핵치료과정중출현약물성시신경염적림상특점。 　　결과：항결핵약물치료인기적약물성시신경염불다견(17/60000)，이구후시신경염다견，인기시신경염적항결핵약물주요시을알정순，기차시이연정、련매소。명학진단후급시정용여시신경염상관적결핵약，병근거병정급여보충유생소，확장혈관，격소등치료，환자적시력도유불동정도적제고。 　　결론：재사용항결핵약기간요주의환자시력변화정황출현돌발시력하강응작안과검사，병급시급여간예，방지실명적엄중후과。
To summarize the clinical characters of optic neuritis caused by antituberculosis drugs, and to discuss the prevention countermeasures. ● METHODS: The clinical characters of optic neuritis caused by antituberculosis drugs among those outpatients and ward patients from January 2003 to January 2013 were reviewed and analyzed. ● RESULTS: Optic neuritis caused by antituberculosis drugs was rare ( 17 / 60000 ), while retrobulbar neuritis was common. The drugs inducing optical neuritis were mainly ethambutol, followed by isoniazid and streptomycin. The vision of patients would have different degrees of improvement via the following treatment after specific diagnosis, i. e. , timely stopping the tuberculosis medicine associated with optic neuritis, and taking vitamin supplements, dilating blood vessels and applying hormone therapy according to the illness. ●CONCLUSlON: We should pay attention to the change of the vision of patients during the usage of antituberculosis drugs. ln the case of sudden eyesight deterioration, ophthalmology examination and timely treatment are advised preventing blindness.