临床荟萃
臨床薈萃
림상회췌
CLINICAL FOCUS
2014年
9期
992-994
,共3页
肺疾病,慢性阻塞性%影响因素分析%logistic 模型
肺疾病,慢性阻塞性%影響因素分析%logistic 模型
폐질병,만성조새성%영향인소분석%logistic 모형
pulmonary disease,chronic obstructive%influencing factors%logistic model
目的:探讨慢性阻塞性肺疾病急性加重(AECOPD)患者在住院期间或出院1天内导致死亡的危险因素,为降低 AECOPD 病死率提供科学的建议。方法选择我院就诊的 AECOPD 患者126例,根据住院期间是否发生死亡分为死亡组(36例)和好转组(90例)。比较两组患者人口学特征、血常规、肺功能、血气分析、C 反应蛋白(CRP)和并发疾病等相关指标;分析影响 AECOPD 患者住院病死率的因素。结果 APOPD 患者126例中,死亡36例,好转90例。两组患者 COPD 综合评级高风险比例、CRP 水平、血红蛋白、白蛋白、淋巴细胞计数、二氧化碳分压(PaCO2)、缺血性心脏病和肺源性心脏病比较,差异具有统计学意义(P <0.05)。高 CRP(OR =3.126,95% CI =1.345~7.265)、高碳酸血症(OR =3.012,95% CI =1.234~7.352)、低淋巴细胞计数(OR =2.341,95% CI =1.084~5.056)、慢性肺源性心脏病(OR =2.510,95% CI =1.203~5.237)是住院 APOPD 患者发生死亡的独立危险因素。结论高 CRP、高碳酸血症、低淋巴细胞计数、并发慢性肺源性心脏病是影响住院 AECOPD 患者发生死亡的独立危险因素。
目的:探討慢性阻塞性肺疾病急性加重(AECOPD)患者在住院期間或齣院1天內導緻死亡的危險因素,為降低 AECOPD 病死率提供科學的建議。方法選擇我院就診的 AECOPD 患者126例,根據住院期間是否髮生死亡分為死亡組(36例)和好轉組(90例)。比較兩組患者人口學特徵、血常規、肺功能、血氣分析、C 反應蛋白(CRP)和併髮疾病等相關指標;分析影響 AECOPD 患者住院病死率的因素。結果 APOPD 患者126例中,死亡36例,好轉90例。兩組患者 COPD 綜閤評級高風險比例、CRP 水平、血紅蛋白、白蛋白、淋巴細胞計數、二氧化碳分壓(PaCO2)、缺血性心髒病和肺源性心髒病比較,差異具有統計學意義(P <0.05)。高 CRP(OR =3.126,95% CI =1.345~7.265)、高碳痠血癥(OR =3.012,95% CI =1.234~7.352)、低淋巴細胞計數(OR =2.341,95% CI =1.084~5.056)、慢性肺源性心髒病(OR =2.510,95% CI =1.203~5.237)是住院 APOPD 患者髮生死亡的獨立危險因素。結論高 CRP、高碳痠血癥、低淋巴細胞計數、併髮慢性肺源性心髒病是影響住院 AECOPD 患者髮生死亡的獨立危險因素。
목적:탐토만성조새성폐질병급성가중(AECOPD)환자재주원기간혹출원1천내도치사망적위험인소,위강저 AECOPD 병사솔제공과학적건의。방법선택아원취진적 AECOPD 환자126례,근거주원기간시부발생사망분위사망조(36례)화호전조(90례)。비교량조환자인구학특정、혈상규、폐공능、혈기분석、C 반응단백(CRP)화병발질병등상관지표;분석영향 AECOPD 환자주원병사솔적인소。결과 APOPD 환자126례중,사망36례,호전90례。량조환자 COPD 종합평급고풍험비례、CRP 수평、혈홍단백、백단백、림파세포계수、이양화탄분압(PaCO2)、결혈성심장병화폐원성심장병비교,차이구유통계학의의(P <0.05)。고 CRP(OR =3.126,95% CI =1.345~7.265)、고탄산혈증(OR =3.012,95% CI =1.234~7.352)、저림파세포계수(OR =2.341,95% CI =1.084~5.056)、만성폐원성심장병(OR =2.510,95% CI =1.203~5.237)시주원 APOPD 환자발생사망적독립위험인소。결론고 CRP、고탄산혈증、저림파세포계수、병발만성폐원성심장병시영향주원 AECOPD 환자발생사망적독립위험인소。
Objective To investigate the influencing factors for hospitalization or one day after hospital discharge mortality of elderly patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD)and to provide scientific suggestions for AECOPD prevention.Methods A total of 126 patients with AECOPD admitted for therapy in our hospital were divided into death group and improvement group according to whether they suffered from death during hospitalization.The demographic characters,blood routine parameters,pulmonary function,blood gas analysis,C reactive protein(CRP)and concurrent disease were compared between two groups.Additionally,the in-hospital mortality in patients with AECOPD were analyzed.Results Among 126 patients,36 cases died during hospitalization while another 90 cases improved.The proportion of high exacerbation risk,CRP level,hemoglobin, albumin,lymphocyte count,PaCO2 ,ischemic heart disease and pulmonary heart disease were statistically significant compared with the control group (P < 0.05 ).High sensitive C-reactive protein(OR = 3.126,95% CI = 1.345-7.265),hypercapnia(OR = 3.012,95% CI = 1.234-7.352),low lymphocyte count(OR = 2.341,95% CI = 1.084-5.056),chronic pulmonary heart disease (OR = 2.510,95% CI = 1.203-5.237)were independent risk factors for AECOPD mortality.Conclusion The elevated CRP,hypercapnia,CPHD and lymphocyte count are influencing mortality factors for in-patients with AECOPD.