临床荟萃
臨床薈萃
림상회췌
CLINICAL FOCUS
2014年
9期
982-984,985
,共4页
糖尿病,2 型%冠状动脉疾病%颈动脉疾病%诊断价值
糖尿病,2 型%冠狀動脈疾病%頸動脈疾病%診斷價值
당뇨병,2 형%관상동맥질병%경동맥질병%진단개치
diabetes mellitus,type 2%coronary disease%carotid artery disease%diagnostic value
目的：探究最大颈动脉内膜中层厚度（cIMT）对2型糖尿病（T2DM）伴发冠心病患者的诊断价值。方法对40例 T2DM 伴发冠心病患者（观察组）与50例 T2DM 无伴发冠心病患者（对照组）的最大 cIMT 及实验室指标进行检测，分析 T2DM 伴发冠心病与最大 cIMT 的相关性。结果观察组患者的最大 cIMT、高密度脂蛋白水平及年龄分别为1．31（1．11，1．42）mm、（1．02±0．12）mmol/L、（64．52±7．25）岁，与对照组的1．00（0．79，1．25）mm、（1．18±0．32）mmol/L、（55．58±10．02）岁，差异均有统计学意义（P ＜0．05或＜0．01）；经单因素筛选与多元回归分析后，患者的年龄、最大 cIMT 均是 T2DM 伴发冠心病的独立危险因素（P ＜0．05）；受试者工作特征曲线分析显示，最大cIMT 对 T2DM 伴发冠心病的诊断特异性与敏感性分别为70．0％与75．0％。结论 T2DM 伴发冠心病与最大 cIMT有关，cIMT 对冠心病患者具有较高的独立预测价值，可作为 T2DM 患者伴发冠心病的诊断指标。
目的：探究最大頸動脈內膜中層厚度（cIMT）對2型糖尿病（T2DM）伴髮冠心病患者的診斷價值。方法對40例 T2DM 伴髮冠心病患者（觀察組）與50例 T2DM 無伴髮冠心病患者（對照組）的最大 cIMT 及實驗室指標進行檢測，分析 T2DM 伴髮冠心病與最大 cIMT 的相關性。結果觀察組患者的最大 cIMT、高密度脂蛋白水平及年齡分彆為1．31（1．11，1．42）mm、（1．02±0．12）mmol/L、（64．52±7．25）歲，與對照組的1．00（0．79，1．25）mm、（1．18±0．32）mmol/L、（55．58±10．02）歲，差異均有統計學意義（P ＜0．05或＜0．01）；經單因素篩選與多元迴歸分析後，患者的年齡、最大 cIMT 均是 T2DM 伴髮冠心病的獨立危險因素（P ＜0．05）；受試者工作特徵麯線分析顯示，最大cIMT 對 T2DM 伴髮冠心病的診斷特異性與敏感性分彆為70．0％與75．0％。結論 T2DM 伴髮冠心病與最大 cIMT有關，cIMT 對冠心病患者具有較高的獨立預測價值，可作為 T2DM 患者伴髮冠心病的診斷指標。
목적：탐구최대경동맥내막중층후도（cIMT）대2형당뇨병（T2DM）반발관심병환자적진단개치。방법대40례 T2DM 반발관심병환자（관찰조）여50례 T2DM 무반발관심병환자（대조조）적최대 cIMT 급실험실지표진행검측，분석 T2DM 반발관심병여최대 cIMT 적상관성。결과관찰조환자적최대 cIMT、고밀도지단백수평급년령분별위1．31（1．11，1．42）mm、（1．02±0．12）mmol/L、（64．52±7．25）세，여대조조적1．00（0．79，1．25）mm、（1．18±0．32）mmol/L、（55．58±10．02）세，차이균유통계학의의（P ＜0．05혹＜0．01）；경단인소사선여다원회귀분석후，환자적년령、최대 cIMT 균시 T2DM 반발관심병적독립위험인소（P ＜0．05）；수시자공작특정곡선분석현시，최대cIMT 대 T2DM 반발관심병적진단특이성여민감성분별위70．0％여75．0％。결론 T2DM 반발관심병여최대 cIMT유관，cIMT 대관심병환자구유교고적독립예측개치，가작위 T2DM 환자반발관심병적진단지표。
Objective To investigate the diagnostic value of carotid intima-media thickness(cIMT)for coronary heart disease in patients with type 2 diabetes mellitus(T2DM).Methods The maximum cIMT and laboratory indexes in 40 T2DM patients with coronary heart disease (observation group)and 50 T2DM patients without coronary heart disease(control group)were measured respectively,and the relationship between maximum cIMT and T2DM with coronary heart disease was analyzed.Results The maximum cIMT,high-density lipoprotein cholesterol level and age of the observation group were 1.31 (1.11,1.42)mm,(1.02 ± 0.12)mmol/L and (64.52 ± 7.25)years(P < 0.05), which were respectively significantly different from 1.00(0.79,1.25)mm,(1.18±0.32)mmol/L and (55.58±10.02) years of the control group(P < 0.05 or < 0.01).After single factor screening and multiple regression analysis,the patients'maximum cIMT was the independent risk of T2DM with coronary heart disease (P <0.05).ROC analysis showed the specificity and sensitivity of the diagnosis of maximum cIMT in T2DM with coronary heart disease were 70.0% and 75.0%,respectively.Conclusion T2DM with coronary heart disease is associated with the maximum cIMT,cIMT has high independent predictive value as a diagnostic indicator for T2DM patients with coronary heart disease.
