CAJ | 학술논문

多巴胺修饰的不锈钢丝表面原位合成得到聚(甲基丙烯酸缩水甘油酯-乙二醇二甲基丙烯酸酯)( poly( GMA-EGDMA))材料,经硫酸改性后作为固相微萃取涂层,建立检测水样中4种药品及个人护理用品( PPCPs)的固相微萃取-液相色谱联用分析方法。在优化实验条件下取3 mL水样调节至pH 5.5,在30℃下,搅拌萃取60 min,乙腈-0.1%甲酸(25∶75, V/V)解吸30 min后,HPLC进样分析,实验结果表明,该涂层材料对4种PPCPs具有较好的萃取效果,2~200μg/L浓度范围内线性关系良好,相关系数均大于0.997,方法检出限(S/N=3)范围为0.5~5.0μg/L,相对标准偏差在4.1%~11.9%之间；加标实验回收率为70.6%~105.5%。本方法前处理简单、绿色环保、回收率高、精密度好,可用于实际水样中4种PPCPs的检测。
다파알수식적불수강사표면원위합성득도취(갑기병희산축수감유지-을이순이갑기병희산지)( poly( GMA-EGDMA))재료,경류산개성후작위고상미췌취도층,건립검측수양중4충약품급개인호리용품( PPCPs)적고상미췌취-액상색보련용분석방법。재우화실험조건하취3 mL수양조절지pH 5.5,재30℃하,교반췌취60 min,을정-0.1%갑산(25∶75, V/V)해흡30 min후,HPLC진양분석,실험결과표명,해도층재료대4충PPCPs구유교호적췌취효과,2~200μg/L농도범위내선성관계량호,상관계수균대우0.997,방법검출한(S/N=3)범위위0.5~5.0μg/L,상대표준편차재4.1%~11.9%지간；가표실험회수솔위70.6%~105.5%。본방법전처리간단、록색배보、회수솔고、정밀도호,가용우실제수양중4충PPCPs적검측。
A poly( GMA-EGDMA) coated SPME fiber was prepared using an in-situ polymerization by direct bonding to the surface of a polydopamine-modified stainless steel wire. Then the fiber was modified by sulfuric acid. A novel solid phase microextraction coating coupled to high performance liquid chromatography ( HPLC) method based on the as-prepared fiber was developed for the determination of four pharmaceuticals and personal care products ( PPCPs) in water samples. The influences of extraction parameters, including pH, extraction time, extraction temperature and salt addition were investigated. 3 mL water sample was extracted by the as-prepared fiber for 60 min at 30 ℃, and then desorbed with mobile phase for 30 min, respectively. Desorption solution was analyzed by HPLC-DAD ( diode array detection ) . The results indicated that the extraction yield of the fiber was good for four PPCPs. The linear correlation coefficients were>0. 997 with the linear range of 2-200 μg/L. The limits of detection (S/N=3) were 0. 5-5 μg/L with RSD (n=5) of 4. 1%-11. 9%. The recoveries of four PPCPs at spiked level of 20, 50, 100 μg/L were within the range of 70. 6%-105. 5%. The results showed that this method was easy, green, accurate and precise, and could be used to assay the four PPCPs in real water samples.