海南医学
海南醫學
해남의학
HAINAN MEDICAL JOURNAL
2014年
13期
1988-1990
,共3页
呼吸窘迫综合征%早产儿%鼻塞持续气道正压给氧%经鼻间歇正压通气%肺表面活性物质
呼吸窘迫綜閤徵%早產兒%鼻塞持續氣道正壓給氧%經鼻間歇正壓通氣%肺錶麵活性物質
호흡군박종합정%조산인%비새지속기도정압급양%경비간헐정압통기%폐표면활성물질
Respiratory distress syndrome%Preterm infant%Nasal continuous positive airway pressure (CPAP)%Nasal intermittent positive pressure ventilation (NIPPV)%Pulmonary surfactant
目的：观察非侵入性呼吸支持对新生儿呼吸窘迫综合征的临床疗效。方法将胎龄≤35周，且符合新生儿呼吸窘迫综合征(NRDS)诊断标准的82例早产儿作为观察对象。尽早给予NCPAP支持，若失败则改用NIPPV支持，必要时使用PS或机械通气。结果82例观察对象全部使用了NCPAP，其中19例因效果不明显改用了NIPPV，66例使用了PS；72 h内无一例使用有创机械通气，但有4例患儿后期因合并院内感染或BPD使用了气管插管机械通气；82例中1例因先天性肠闭锁于生后第二天转外科手术治疗，1例因经济原因于第2天签字出院，其余80例均痊愈出院。结论无创呼吸支持用于治疗早产儿NRDS疗效肯定，部分患儿如果尽早使用NCPAP或NIPPV，可以不使用PS。因无创呼吸支持经济便捷，值得临床推广应用。
目的：觀察非侵入性呼吸支持對新生兒呼吸窘迫綜閤徵的臨床療效。方法將胎齡≤35週，且符閤新生兒呼吸窘迫綜閤徵(NRDS)診斷標準的82例早產兒作為觀察對象。儘早給予NCPAP支持，若失敗則改用NIPPV支持，必要時使用PS或機械通氣。結果82例觀察對象全部使用瞭NCPAP，其中19例因效果不明顯改用瞭NIPPV，66例使用瞭PS；72 h內無一例使用有創機械通氣，但有4例患兒後期因閤併院內感染或BPD使用瞭氣管插管機械通氣；82例中1例因先天性腸閉鎖于生後第二天轉外科手術治療，1例因經濟原因于第2天籤字齣院，其餘80例均痊愈齣院。結論無創呼吸支持用于治療早產兒NRDS療效肯定，部分患兒如果儘早使用NCPAP或NIPPV，可以不使用PS。因無創呼吸支持經濟便捷，值得臨床推廣應用。
목적：관찰비침입성호흡지지대신생인호흡군박종합정적림상료효。방법장태령≤35주，차부합신생인호흡군박종합정(NRDS)진단표준적82례조산인작위관찰대상。진조급여NCPAP지지，약실패칙개용NIPPV지지，필요시사용PS혹궤계통기。결과82례관찰대상전부사용료NCPAP，기중19례인효과불명현개용료NIPPV，66례사용료PS；72 h내무일례사용유창궤계통기，단유4례환인후기인합병원내감염혹BPD사용료기관삽관궤계통기；82례중1례인선천성장폐쇄우생후제이천전외과수술치료，1례인경제원인우제2천첨자출원，기여80례균전유출원。결론무창호흡지지용우치료조산인NRDS료효긍정，부분환인여과진조사용NCPAP혹NIPPV，가이불사용PS。인무창호흡지지경제편첩，치득림상추엄응용。
Objective To evaluate the efficacy and safety of noninvasive respiratory support for preterm in-fants with respiratory distress syndrome. Methods Chart data of inborn infants≤35 weeks with respiratory distress syndrome (RDS) in the period 1st Aug 2011 to 31st July 2013 were reviewed. Nasal continuous positive airway pressure (NCPAP) was given as early as possible when RDS was suspected, while nasal intermittent positive pressure ventila-tion (NIPPV) was given to those failed NCPAP. Mechanical ventilation (MV) or surfactant would be given as neces-sary. Results Eighty-two preterm infants were enrolled, all of which received NCPAP in 72 hours of age, and nine-teen received NIPPV due to failure of CPAP. No infants needed MV in their first 72 hours of life, but 4 infants needed in the later due to nosocomial infection or bronchopulmonary dysplasia (BPD). Eighty of 82 infants recovered except one transferred to surgery departmemt due to intestinal atresia and another one gave up due to economical reason. Conclusion Noninvasive respiratory support is successful and safe for preterm infants with respiratory distress syn-drome, and NIPPV is more effective than NCPAP. And the earlier the use, the better the outcome.
