CAJ | 학술논문

目的：探讨腹腔镜下卵巢巧克力囊肿剔除术后联合应用促性腺激素释放激素激动剂（GnRHa）的疗效及其对卵巢功能的影响。方法60例卵巢巧克力囊肿患者随机分为两组各30例，对照组予单纯腹腔镜下囊肿剔除术，观察组术后联合GnRHa治疗，比较两组患者术后疗效及血清雌二醇(E2)与卵巢基础窦状卵泡数(AFC)的差异。结果治疗后观察组总有效率、痛经缓解率分别为93.33%和80.00%，均明显高于对照组的73.33%、53.33%，观察组复发率为3.33%，显著低于对照组的20.00%，以上各项指标比较差异均有统计学意义(P<0.05)；两组患者治疗后AFC变化均差异无统计学意义(P>0.05)，血清E2较治疗前显著下降，且观察组小于对照组，差异有统计学意义(P<0.05)。结论腹腔镜术后联合GnRHa治疗卵巢巧克力囊肿可显著提高临床疗效，降低术后复发率，且未明显损伤卵巢功能。
목적：탐토복강경하란소교극력낭종척제술후연합응용촉성선격소석방격소격동제（GnRHa）적료효급기대란소공능적영향。방법60례란소교극력낭종환자수궤분위량조각30례，대조조여단순복강경하낭종척제술，관찰조술후연합GnRHa치료，비교량조환자술후료효급혈청자이순(E2)여란소기출두상란포수(AFC)적차이。결과치료후관찰조총유효솔、통경완해솔분별위93.33%화80.00%，균명현고우대조조적73.33%、53.33%，관찰조복발솔위3.33%，현저저우대조조적20.00%，이상각항지표비교차이균유통계학의의(P<0.05)；량조환자치료후AFC변화균차이무통계학의의(P>0.05)，혈청E2교치료전현저하강，차관찰조소우대조조，차이유통계학의의(P<0.05)。결론복강경술후연합GnRHa치료란소교극력낭종가현저제고림상료효，강저술후복발솔，차미명현손상란소공능。
Objective To investigate the clinical effect of endometriotic cystectomy under laparoscopy com-bined with GnRHa and its influence on ovarian function. Methods Sixty patients with endometriotic cyst were ran-domly divided into control group and observation group. The patients in the control group were treated with simply laparoscopic cyst excision, while the patients in the observation group were treated additional GnRHa. The therapeutic efficacies and differences in postoperative serum estradiol (E2) and antral basis follicle count (AFC) between the two groups were analyzed. Results After treatment, there were statistically significant differences in the rates of total ef-fect, dysmenorrheal relief and recurrence between the observation group and the control group (93.33% vs 73.33%, 80.00%vs 53.33%, and 3.33%vs 20.00%respectively, P<0.05). There was no statistical difference in the change of AFC between the two groups (P>0.05). After treatment, E2 in serum significantly decreased, which in the observation group was statistically significantly lower than that in the control group (P<0.05). Conclusion Laparoscopic surgery combined with GnRHa treatment in ovarian chocolate cysts can significantly improve the clinical outcome and reduce the recurrence rate, with no obvious damage on ovarian function.