CAJ | 학술논문

晚期乳腺癌包括局部病变较晚、无法直接手术的患者和初诊时已有远地转移M1及手术后的复发转移患者。目前，我们国家对于这些患者的处理非常混乱，往往初始治疗与首次接诊医生的专业范围大有相关。孤立病灶的晚期乳腺癌患者，全身播散背景已成定势，全身药物治疗才是最重要的治疗手段。对于已经全身转移的晚期乳腺癌患者来讲，是否加用局部病灶切除，需根据患者的全身情况而定。任何一种治疗的选择及安排都应按照药品临床试验管理规范（GCP）原则进行，以期最大限度改善生活质量及生存时间。
만기유선암포괄국부병변교만、무법직접수술적환자화초진시이유원지전이M1급수술후적복발전이환자。목전，아문국가대우저사환자적처리비상혼란，왕왕초시치료여수차접진의생적전업범위대유상관。고립병조적만기유선암환자，전신파산배경이성정세，전신약물치료재시최중요적치료수단。대우이경전신전이적만기유선암환자래강，시부가용국부병조절제，수근거환자적전신정황이정。임하일충치료적선택급안배도응안조약품림상시험관리규범（GCP）원칙진행，이기최대한도개선생활질량급생존시간。
Advanced breast cancer ,including patients with local advanced lesion ,inoperable ones ,with metastasis at the first visit ,or recurrence and metastasis after surgery .At present ,in our country the treatment for these patients is very chaotic .The initial treatment is often associated with the first-visit doctors'professional range .For the isolated lesion of patients with advanced breast cancer ,the whole body spread background has been set ,so systemic drug therapy is the most important treatment .For advanced breast cancer spreading to the whole body ,whether or not combine with local lesion resection should be considered according to the patient's general condition .Choice and arrangement of any kind of treatment should be in accordance with the principles of GCP ,in order to maximize the patient's overall survival and reduce the risk of disease progression .