CAJ | 학술논문

目的：研究2型糖尿病合并冠心病患者的临床特点，为进一步指导治疗提供依据。方法对50例糖尿病合并冠心病患者、50例单纯冠心病患者、单纯糖尿病患者50例及50名健康对照者的性别、年龄、病程、体质量指数（BMI）、血压、空腹血糖、糖化血红蛋白（HbA1c）、血脂、空腹胰岛素等指标进行对照，并将糖尿病合并冠心病患者冠状动脉病情状况与单纯冠心病患者进行对比。结果糖尿病合并冠心病组和单纯冠心病组与对照组相比，BMI、血压、甘油三酯（TG）、总胆固醇（TC）、低密度脂蛋白胆固醇（LDL）、高密度脂蛋白胆固醇（HDL）存在差别，糖尿病合并冠心病组空腹血糖、HbA1c、胰岛素水平、TG均较单纯冠心病组及对照组高，糖尿病合并冠心病组较单纯冠心病组冠状动脉病变更加广泛，狭窄程度更重。结论血压、TG、TC、LDL、HDL、BMI、HbA1c、空腹胰岛素水平是2型糖尿病患者合并冠心病的危险因素，2型糖尿病患者合并冠心病冠状动脉病变更加广泛，狭窄程度更为严重。
목적：연구2형당뇨병합병관심병환자적림상특점，위진일보지도치료제공의거。방법대50례당뇨병합병관심병환자、50례단순관심병환자、단순당뇨병환자50례급50명건강대조자적성별、년령、병정、체질량지수（BMI）、혈압、공복혈당、당화혈홍단백（HbA1c）、혈지、공복이도소등지표진행대조，병장당뇨병합병관심병환자관상동맥병정상황여단순관심병환자진행대비。결과당뇨병합병관심병조화단순관심병조여대조조상비，BMI、혈압、감유삼지（TG）、총담고순（TC）、저밀도지단백담고순（LDL）、고밀도지단백담고순（HDL）존재차별，당뇨병합병관심병조공복혈당、HbA1c、이도소수평、TG균교단순관심병조급대조조고，당뇨병합병관심병조교단순관심병조관상동맥병변경가엄범，협착정도경중。결론혈압、TG、TC、LDL、HDL、BMI、HbA1c、공복이도소수평시2형당뇨병환자합병관심병적위험인소，2형당뇨병환자합병관심병관상동맥병변경가엄범，협착정도경위엄중。
Objective To make a research of clinical characters of type 2 diabetes patients with coronary heart disease(CHD) and to guide the further treatment for such patients .Methods Four groups are selected for research .Group 1 is composed of 50 diabetes patients with CHD .Group 2 is composed of 50 pure CHD patients . Group 3 is composed of pure diabetes patients .Group 4 is composed of 50 health candidates .Many aspects are compared including gender ,age ,illness course ,BMI ,BP ,fast blood glucose and fast insulin .Analysing is made by comparing group 1 and group 3.Results Both group 1 and group 3 have statistic difference with group 4 in the aspects of BMI ,BP ,TG ,TC ,LDL and HDL .Some data of group 1 are higher than those of group 3 and group 4 including fast blood glucose ,HbA1c ,insulin level and TG .The narrow situation of coronary artery in group 1 is worse than that of group 3 including size and extent .Conclusion The risk factors for type 2 diabetes with CHD in-cluded BP ,TG ,TC ,LDL ,HDL ,BMI ,HbA1c and fast insulin .When combined with CHD in type 2 diabetes pa-tients ,the pathological changes of coronary artery are more extensive and worse.