CAJ | 학술논문

目的：为规范医院外科围术期抗菌药物预防性应用与管理，探索合理干预途径。方法选取普外科甲状腺手术、乳腺手术、腹股沟疝修补术3种Ⅰ类切口手术，2011-07至2011-09的出院病例为干预前组（基线调查组），2012-07至2012-09，以及2013-07至2013-09的出院病例为干预后1、2组，对干预前后3组预防使用抗菌药物的合理性进行干预对照研究。结果共调查病历348份，2011-2013年抗菌药物预防使用率依次为96．2％、33．6％、6．9％（ P＜0．05）。3种Ⅰ类切口手术3年的抗菌药物预防使用率分别为：甲状腺100％、3．8％、2．9％；腹股沟疝91．8％、55．5％、12．8％；乳腺100％、61．9％、8．7％。结论通过制订干预措施能有效提高医院抗菌药物临床合理应用水平。
목적：위규범의원외과위술기항균약물예방성응용여관리，탐색합리간예도경。방법선취보외과갑상선수술、유선수술、복고구산수보술3충Ⅰ류절구수술，2011-07지2011-09적출원병례위간예전조（기선조사조），2012-07지2012-09，이급2013-07지2013-09적출원병례위간예후1、2조，대간예전후3조예방사용항균약물적합이성진행간예대조연구。결과공조사병력348빈，2011-2013년항균약물예방사용솔의차위96．2％、33．6％、6．9％（ P＜0．05）。3충Ⅰ류절구수술3년적항균약물예방사용솔분별위：갑상선100％、3．8％、2．9％；복고구산91．8％、55．5％、12．8％；유선100％、61．9％、8．7％。결론통과제정간예조시능유효제고의원항균약물림상합리응용수평。
Objective To standardise the antimicrobial prophylaxis ( AMP) during perioperative period of surgical operations in this hospital and explore reasonable measures of intervention .Methods Patients who underwent three type I incisions in general sur-gery:including thyroid , breast and inguinal hermia repair surgery , were recruited .The patients dismissed from July to September of year 2011 were taken as pre-intervention group , and those in year 2012 and 2013 as post-intervention group .The rationaly of antibiolic prophylaxis between pre-intervention group and post-intervention group were compared control study .Results A total of 348 cases were investigated.The utilization rate of antimicrobial prophylaxis from year 2011 to 2013 were 96.2%, 33.6%, 6.9%, respectively. Utilization rates of antimicrobial prophylaxis in the three type I incision surgery during the three years were as follows :100%, 3.8%, and 2.9%for thyroid surgery;91.8%, 55.5%, and 12.8% for inguinal hermia repair surgery;100%, 61.9%, and 8.7% for breast surgery .Conclusions The intervening measures improve effectively the reasonable use of antibiotics in clinic .