CAJ | 학술논문

Maf家族基因编码是一类含有碱性结构域和b-Zip的转录因子,Maf基因编码的蛋白在血细胞发生、胰腺分化、眼睛晶状体发育等多个过程中起重要作用,但目前该基因家族的进化并不清楚。本文首先搜索了不同基因组中的可能的Maf家族基因,对其染色体定位、基因结构、编码蛋白的功能域等进行分析,并构建系统进化树研究了该基因家族的进化。
Maf가족기인편마시일류함유감성결구역화b-Zip적전록인자,Maf기인편마적단백재혈세포발생、이선분화、안정정상체발육등다개과정중기중요작용,단목전해기인가족적진화병불청초。본문수선수색료불동기인조중적가능적Maf가족기인,대기염색체정위、기인결구、편마단백적공능역등진행분석,병구건계통진화수연구료해기인가족적진화。
Maf family proteins are a large number of transcriptional factors which include a characteristic basic region and a leucine zipper ( b-Zip ) motif. They play key roles in the hemacytopoiesis, pancreatic differentiation,and the lens development of eyes. However,the evolutionary process of Maf gene family is un-known. In this study,genome-wide survey of Maf gene family was performed,and chromosome location,gene structure,conserved protein motifs of Mafs were analyzed. To explore the evolution of Maf gene family with the struction of phylogenetic tree.