CAJ | 학술논문

特发性肺纤维化（IPF）为一种慢性、进展性、纤维化型间质性肺炎的特殊类型，目前尚缺乏有效、安全的治疗手段。近年来，中医药手段治疗IPF的临床试验开展较多，但评价标准、指标的选取却各有不同，缺乏统一的、规范的认识。本文从病证结合诊疗模式的角度，概括和整理目前广泛应用的评价手段，结合最新诊疗规范的要求，提出了该病的疗效评价体系框架，并对框架内重要指标、方法进行阐述。以期由此完善临床试验设计，为今后的循证医学研究提供高质量的“证据链”。
특발성폐섬유화（IPF）위일충만성、진전성、섬유화형간질성폐염적특수류형，목전상결핍유효、안전적치료수단。근년래，중의약수단치료IPF적림상시험개전교다，단평개표준、지표적선취각각유불동，결핍통일적、규범적인식。본문종병증결합진료모식적각도，개괄화정리목전엄범응용적평개수단，결합최신진료규범적요구，제출료해병적료효평개체계광가，병대광가내중요지표、방법진행천술。이기유차완선림상시험설계，위금후적순증의학연구제공고질량적“증거련”。
Idiopathic pulmonary fibrosis (IPF) is defined as a specific form of chronic and progressive fibrosing inter-stitial pneumonia. Till now, it is lack of effective and safe treatment. In recent years, more and more clinical trials of traditional Chinese medicine (TCM) have been conducted with different evaluation criteria and indexes. The knowl-edge is disunity and unsystematic. From the perspective of combination of disease and TCM syndrome model, this ar-ticle summarized and organized the current data and medical standards, and then come up with the new evaluation system of clinical effect and describe important indexes and methods. This article was aimed to improve the clinical trial design and provide high quality evidences for evidence-based medicine.