CAJ | 학술논문

目的：探讨对184例女性生殖道解脲脲原体感染者进行药物敏感性试验的结果分析。方法：将2013年1月～2014年1月期间唐山市眼科医院妇科门诊收治的184例女性生殖道解脲脲原体阳性患者的临床资料进行回顾性研究。取这些患者的阴道分泌物，使用病原体鉴定药敏试剂盒进行药敏试验，并对其试验结果进行分析。结果：这184例患者感染的病原体对四环素的敏感率为92.4%，对强力霉素的敏感率为88.0%，对美满霉素的敏感率为93.5%，对交沙霉素的敏感率为90.2%，对司帕沙星的敏感率为95.7%，对红霉素的耐药率为96.2%，对罗红霉素的耐药率为75.0%，对壮观霉素的耐药率为79.3%，对阿奇霉素的耐药率为76.6%。结论：四环素类抗生素可作为治疗女性生殖道解脲脲原体感染患者的首选药物，交沙霉素可作为治疗女性生殖道解脲脲原体感染患者的经验用药。
목적：탐토대184례녀성생식도해뇨뇨원체감염자진행약물민감성시험적결과분석。방법：장2013년1월～2014년1월기간당산시안과의원부과문진수치적184례녀성생식도해뇨뇨원체양성환자적림상자료진행회고성연구。취저사환자적음도분비물，사용병원체감정약민시제합진행약민시험，병대기시험결과진행분석。결과：저184례환자감염적병원체대사배소적민감솔위92.4%，대강력매소적민감솔위88.0%，대미만매소적민감솔위93.5%，대교사매소적민감솔위90.2%，대사파사성적민감솔위95.7%，대홍매소적내약솔위96.2%，대라홍매소적내약솔위75.0%，대장관매소적내약솔위79.3%，대아기매소적내약솔위76.6%。결론：사배소류항생소가작위치료녀성생식도해뇨뇨원체감염환자적수선약물，교사매소가작위치료녀성생식도해뇨뇨원체감염환자적경험용약。
Objective: In order to provide basis for clinical rational drug use, we analyze 184 ureaplasma urealyticum positive specimens collected from gynecological patients in Tangshan eye hospital from January 2012 to January 2013. METHODS: drug sensitivity tests through Mycoplasma identification and drug susceptibility kits.RESULT: Drug sensitivity of Tetracycline, doxycycline, minocycline, josamycin and sparfloxacin respectively are 92.4%, 88.0%, 93.5%, 90.2% and 95.7%; drug resistency rates of Erythromycin, roxithromycin, spectinomycin and azithromycin respectively are 96.2%, 75.0%, 79.3% and 76.6%. CONCLUSIONS: Tetracycline antibiotic is preferred drug for Ureaplasma urealyticum infections in reproductive tract; Josamycin is experienced application of Ureaplasma urealyticum infection; Though Quinolones are safe and have broad antibacterial spectrum in recent years, its increasing drug resistance rate limit its clinical application.