中国医药科学
中國醫藥科學
중국의약과학
CHINA MEDICINE AND PHARMACY
2014年
21期
196-198
,共3页
鼻面罩无创正压通气%呼吸兴奋剂%慢性阻塞性肺病%肺性脑病%疗效
鼻麵罩無創正壓通氣%呼吸興奮劑%慢性阻塞性肺病%肺性腦病%療效
비면조무창정압통기%호흡흥강제%만성조새성폐병%폐성뇌병%료효
Non-invasive positive pressure ventilation%Respiratory stimulant%Chronic obstructive pulmonary disease%Pulmonary encephalopathy%Clinical effect
目的：评价鼻面罩无创正压通气联用呼吸兴奋剂治疗慢阻肺呼吸衰竭合并肺性脑病患者的疗效。方法将68例慢阻肺呼吸竭合并肺性脑病患者随机分为对照组和观察组，分别给予鼻面罩无创正压通气治疗和鼻面罩无创正压通气联用呼吸兴奋剂治疗，评价联合治疗方法的临床疗效。结果两组患者通气3h 后和治疗结束时的 pH、PaO2和 PaCO2较治疗前均明显好转，观察组患者的恢复情况优于对照组（P ＜0.05）。经过治疗后，观察组患者通气有效率85.29%，明显高于对照组（P ＜0.05），气管插管率和胃胀气发生率分别为14.71%和32.35%，低于对照组（P＜0.05），两组患者的住院病死率均为2.94%，差异无统计学意义（P＞0.05）。结论鼻面罩无创正压通气联用呼吸兴奋剂治疗慢阻肺呼吸竭合并肺性脑病的临床效果优于单纯鼻面罩无创正压通气，是一种较好的治疗方法。
目的：評價鼻麵罩無創正壓通氣聯用呼吸興奮劑治療慢阻肺呼吸衰竭閤併肺性腦病患者的療效。方法將68例慢阻肺呼吸竭閤併肺性腦病患者隨機分為對照組和觀察組，分彆給予鼻麵罩無創正壓通氣治療和鼻麵罩無創正壓通氣聯用呼吸興奮劑治療，評價聯閤治療方法的臨床療效。結果兩組患者通氣3h 後和治療結束時的 pH、PaO2和 PaCO2較治療前均明顯好轉，觀察組患者的恢複情況優于對照組（P ＜0.05）。經過治療後，觀察組患者通氣有效率85.29%，明顯高于對照組（P ＜0.05），氣管插管率和胃脹氣髮生率分彆為14.71%和32.35%，低于對照組（P＜0.05），兩組患者的住院病死率均為2.94%，差異無統計學意義（P＞0.05）。結論鼻麵罩無創正壓通氣聯用呼吸興奮劑治療慢阻肺呼吸竭閤併肺性腦病的臨床效果優于單純鼻麵罩無創正壓通氣，是一種較好的治療方法。
목적：평개비면조무창정압통기련용호흡흥강제치료만조폐호흡쇠갈합병폐성뇌병환자적료효。방법장68례만조폐호흡갈합병폐성뇌병환자수궤분위대조조화관찰조，분별급여비면조무창정압통기치료화비면조무창정압통기련용호흡흥강제치료，평개연합치료방법적림상료효。결과량조환자통기3h 후화치료결속시적 pH、PaO2화 PaCO2교치료전균명현호전，관찰조환자적회복정황우우대조조（P ＜0.05）。경과치료후，관찰조환자통기유효솔85.29%，명현고우대조조（P ＜0.05），기관삽관솔화위창기발생솔분별위14.71%화32.35%，저우대조조（P＜0.05），량조환자적주원병사솔균위2.94%，차이무통계학의의（P＞0.05）。결론비면조무창정압통기련용호흡흥강제치료만조폐호흡갈합병폐성뇌병적림상효과우우단순비면조무창정압통기，시일충교호적치료방법。
Objective To evaluate the clinical effect of non-invasive positive pressure ventilation combined with respiratory stimulant in the treatment of COPD patients with respiratory failure and pulmonary encephalopathy. Methods 68 cases of COPD patients with respiratory failure and pulmonary encephalopathy were randomly divided into the observation group and the control group,which were treated with non-invasive positive pressure ventilation therapy and non-invasive positive pressure ventilation combined with respiratory stimulant respectively.Evaluation was given to the clinical curative effect of combined treatment method. Results the pH,PaO2 and PaO2 of patients in both group were significantly improved 3hours after and at the end of the treatment.And the recovery of the observation group was better than that of the control group(P < 0.05).After treatment, ventilation efficiency of the patients in observation group was 85.29%,significantly higher than that in the observation group(P < 0.05);The incidence of endotracheal intubation and bloating were respectively 14.71% and 32.35%,lower than those in the observation group (P < 0.05);The mortality rates of the two groups of patients in hospital were both 2.94%,no significant difference(P > 0.05). Conclusion The clinical effect of non-invasive positive pressure ventilation combined with respiratory stimulant in the treatment of COPD respiratory failure with pulmonary encephalopathy is better than that of the treatment method of sole non-invasive positive pressure ventilation;therefore it is a good treatment method.
