中国医药科学
中國醫藥科學
중국의약과학
CHINA MEDICINE AND PHARMACY
2014年
21期
126-128
,共3页
ICU%痰培养%耐药性
ICU%痰培養%耐藥性
ICU%담배양%내약성
ICU%Sputum culture%Drug resistance
目的：分析重症监护室（ICU）内痰培养致病菌分布情况及对药物的敏感性，指导 ICU 内抗菌药物的合理应用。方法回顾性分析我院 ICU 2010年1月～2013年12月1167例痰标本培养分离出的病原菌及药物敏感性结果。结果共分离病原菌592株，阳性率50.73％。革兰阴性菌401株，占67.74％，革兰阳性菌152株，占25.68％，真菌39株，占6.58％；初次痰培养阳性分离率21.18％，3d 后阳性分离率89.71％，治疗后阳性分离率42.20％，三者之间有明显差异。肺炎克雷伯菌、鲍曼不动杆菌、铜绿假单胞菌、金黄色葡萄球菌为最常见的多重耐药菌，耐药菌有逐年增加的趋势。结论革兰阴性杆菌是 ICU 内肺部感染的主要致病菌，鲍曼不动杆菌、铜绿假单胞菌是最常见的致病菌，且多重耐药现象较严重。在 ICU 住院时间越长感染率越高。预防交叉感染、及时监测病原菌变化及耐药趋势对临床治疗至关重要。
目的：分析重癥鑑護室（ICU）內痰培養緻病菌分佈情況及對藥物的敏感性，指導 ICU 內抗菌藥物的閤理應用。方法迴顧性分析我院 ICU 2010年1月～2013年12月1167例痰標本培養分離齣的病原菌及藥物敏感性結果。結果共分離病原菌592株，暘性率50.73％。革蘭陰性菌401株，佔67.74％，革蘭暘性菌152株，佔25.68％，真菌39株，佔6.58％；初次痰培養暘性分離率21.18％，3d 後暘性分離率89.71％，治療後暘性分離率42.20％，三者之間有明顯差異。肺炎剋雷伯菌、鮑曼不動桿菌、銅綠假單胞菌、金黃色葡萄毬菌為最常見的多重耐藥菌，耐藥菌有逐年增加的趨勢。結論革蘭陰性桿菌是 ICU 內肺部感染的主要緻病菌，鮑曼不動桿菌、銅綠假單胞菌是最常見的緻病菌，且多重耐藥現象較嚴重。在 ICU 住院時間越長感染率越高。預防交扠感染、及時鑑測病原菌變化及耐藥趨勢對臨床治療至關重要。
목적：분석중증감호실（ICU）내담배양치병균분포정황급대약물적민감성，지도 ICU 내항균약물적합리응용。방법회고성분석아원 ICU 2010년1월～2013년12월1167례담표본배양분리출적병원균급약물민감성결과。결과공분리병원균592주，양성솔50.73％。혁란음성균401주，점67.74％，혁란양성균152주，점25.68％，진균39주，점6.58％；초차담배양양성분리솔21.18％，3d 후양성분리솔89.71％，치료후양성분리솔42.20％，삼자지간유명현차이。폐염극뢰백균、포만불동간균、동록가단포균、금황색포도구균위최상견적다중내약균，내약균유축년증가적추세。결론혁란음성간균시 ICU 내폐부감염적주요치병균，포만불동간균、동록가단포균시최상견적치병균，차다중내약현상교엄중。재 ICU 주원시간월장감염솔월고。예방교차감염、급시감측병원균변화급내약추세대림상치료지관중요。
Objective To analysis the distribution and drug sensitivity of the pathogens in sputum culture in intensive care unit(ICU) for guiding the reasonable application of antibacterial drugs. Methods The pathogenic bacteria and drug sensitivity results of 1167 sputum specimens in January 2010 to December 2013 were analyzed retrospectively. Results There were 592 strains of pathogenic bacteria,the positive rate was 50.73%.401 strains of gram negative bacteria,accounted for 67.74%,gram positive bacteria were 152 strains,accounting for 25.68%,39 strains of fungi,accounting for 6.58%;the positive isolation rate was 21.18% In first sputum culture,89.71% after 3 days and 42.20% after treatment.There was significant difference between the three time.Klebsiella pneumoniae,Bauman Acinetobacter,Pseudomonas aeruginosa,Staphylococcus aureus were the most common multi drug resistant bacteria,antibiotic resistant bacteria has increased year by year. Conclusion Gram negative bacilli were the main pathogens of pulmonary infection in ICU,Bauman Acinetobacter,Pseudomonas aeruginosa are the most common pathogenic bacteria,and the multi- resistant phenomenon is serious.The longer time in ICU,the higher infection rate,The prevention of cross infection,timely monitoring the changes of pathogens and drug resistance trend is essential to guide clinical administration.
