中国医药科学
中國醫藥科學
중국의약과학
CHINA MEDICINE AND PHARMACY
2014年
21期
58-60
,共3页
妊娠合并糖尿病%二甲双胍%胰岛素
妊娠閤併糖尿病%二甲雙胍%胰島素
임신합병당뇨병%이갑쌍고%이도소
Gestational diabetes%Metformin%Insulin
目的：探讨二甲双胍与胰岛素治疗妊娠合并糖尿病对妊娠结局的影响。方法回顾性分析确诊为妊娠合并糖尿病孕妇64例的临床资料，31例采用二甲双胍治疗为二甲双胍组，33例患者采用胰岛素治疗为胰岛素组，比较两组临床疗效及妊娠结局。结果胰岛素组孕产妇发生子痫前发病率，体重增加，＜37周分娩比例、空腹血糖显著高于二甲双胍组（P ＜0.05）。胰岛素组围产儿巨大儿、低血糖、黄单症发生率显著高于二甲双胍组（P ＜0.05）。结论二甲双胍治疗妊娠合并糖尿病能够显著改善妊娠结局，降低孕产妇及围产儿并发症。
目的：探討二甲雙胍與胰島素治療妊娠閤併糖尿病對妊娠結跼的影響。方法迴顧性分析確診為妊娠閤併糖尿病孕婦64例的臨床資料，31例採用二甲雙胍治療為二甲雙胍組，33例患者採用胰島素治療為胰島素組，比較兩組臨床療效及妊娠結跼。結果胰島素組孕產婦髮生子癇前髮病率，體重增加，＜37週分娩比例、空腹血糖顯著高于二甲雙胍組（P ＜0.05）。胰島素組圍產兒巨大兒、低血糖、黃單癥髮生率顯著高于二甲雙胍組（P ＜0.05）。結論二甲雙胍治療妊娠閤併糖尿病能夠顯著改善妊娠結跼，降低孕產婦及圍產兒併髮癥。
목적：탐토이갑쌍고여이도소치료임신합병당뇨병대임신결국적영향。방법회고성분석학진위임신합병당뇨병잉부64례적림상자료，31례채용이갑쌍고치료위이갑쌍고조，33례환자채용이도소치료위이도소조，비교량조림상료효급임신결국。결과이도소조잉산부발생자간전발병솔，체중증가，＜37주분면비례、공복혈당현저고우이갑쌍고조（P ＜0.05）。이도소조위산인거대인、저혈당、황단증발생솔현저고우이갑쌍고조（P ＜0.05）。결론이갑쌍고치료임신합병당뇨병능구현저개선임신결국，강저잉산부급위산인병발증。
Objective To discuss effect of metformin and insulin for gestational diabetes on pregnancy outcomes. Methods Clinical data of 64 cases with gestational diabetes were analyzed.31 cases were treated with metformin as metformin group,and 33 cases were treated with insulin as insulin group.Pregnancy outcomes of two groups were compared. Results Preeclampsia rates,weight gain, < 37 weeks maternity,fasting plasma glucose of insulin group were significantly higher than the metformin group(P < 0.05).Perinatal great children,hypoglycemia,yellow single disease incidence of insulin group were significantly higher than metformin group(P < 0.05). Conclusion Metformin for gestational diabetes can improve pregnancy outcomes,and reduce maternal and neonatal complications.
