CAJ | 학술논문

目的：对比分析聚桂醇注射液与无水乙醇治疗单纯性肝囊肿的疗效与安全性。方法将单纯性肝囊肿患者分为聚桂醇组（86例，研究组）与无水乙醇组（80例，对照组），实施在超声引导下穿刺抽液硬化治疗，对比观察两组患者的疗效及不良反应。结果两组均未出现出血、感染等并发症。治疗过程中对照组45例（56.3%）患者出现不同程度疼痛，23例（28.8%）出现醉酒样症状；研究组无明显不适。治疗后1周，对照组20例（25.0%）患者仍有右上腹胀痛，研究组仅9例（10.5%），差异有统计学意义（χ2=6.073，P＜0.05）；随访6个月，聚桂醇组治愈率95.7%，无水乙醇组93.5%，两组间差异无统计学意义（P＞0.05）。结论聚桂醇注射液在肝囊肿硬化治疗中安全有效，值得临床推广应用。
목적：대비분석취계순주사액여무수을순치료단순성간낭종적료효여안전성。방법장단순성간낭종환자분위취계순조（86례，연구조）여무수을순조（80례，대조조），실시재초성인도하천자추액경화치료，대비관찰량조환자적료효급불량반응。결과량조균미출현출혈、감염등병발증。치료과정중대조조45례（56.3%）환자출현불동정도동통，23례（28.8%）출현취주양증상；연구조무명현불괄。치료후1주，대조조20례（25.0%）환자잉유우상복창통，연구조부9례（10.5%），차이유통계학의의（χ2=6.073，P＜0.05）；수방6개월，취계순조치유솔95.7%，무수을순조93.5%，량조간차이무통계학의의（P＞0.05）。결론취계순주사액재간낭종경화치료중안전유효，치득림상추엄응용。
Objective To compare the efficacy and safety of lauromacrogol injection sclerotherapy with ethanol injection sclerotherapy in treating simple liver cysts. Methods A total of 166 patients with simple liver cyst were randomly divided into the lauromacrogol group (study group, n=86) and the absolute alcohol group (control group, n=80). Under ultrasonographic guidance, puncture aspiration of liver cyst was carried out in all patients, which was followed by injection of lauromacrogol for patients in the study group or injection of ethanol for patients in the control group. The therapeutic effect and the side-effect were evaluated. The results were compared between the two groups. Results No serious complications such as bleeding or infection occurred in both groups. During the therapeutic course , 45 patients (56.3%) in the control group felt pain to some degree and 23 patients (28.8%) developed drunk-like symptoms, while no patient in the study group felt any obvious discomfort. One week after sclerotherapy , 20 patients (25%) in the control group complained of distending pain on the right upper abdomen, while only 9 patients (10.5%) in the study group complained of pain, and the difference was statistically significant (χ2= 6.073, P < 0.05). Six months after the treatment, the cure rate of the study group and the control group was 95.7%and 93.5%respectively, and the difference between the two groups was no significant (P > 0.05). Conclusion For the treatment of liver cysts, lauromacrogol injection is safe and effective. Therefore, this technique should be recommended in clinical practice.