国际中医中药杂志
國際中醫中藥雜誌
국제중의중약잡지
INTERNATIONAL JOURNAL OF TRIDITIONAL CHINESE MEDICINE
2014年
8期
695-698
,共4页
路凌%张兰梅%武军%任莉%刘国
路凌%張蘭梅%武軍%任莉%劉國
로릉%장란매%무군%임리%류국
慢性肾功能衰竭%血液透析%营养不良%脾肾气虚证%健脾补肾方
慢性腎功能衰竭%血液透析%營養不良%脾腎氣虛證%健脾補腎方
만성신공능쇠갈%혈액투석%영양불량%비신기허증%건비보신방
Chronic renal failure%Hemodialysis%Malnutrition%Deficiency spleen and kidney%Warming kidney and invigorating spleen
目的：观察健脾补肾方对脾肾气虚型慢性肾功能衰竭血液透析患者营养状况的影响。方法收集2012年6月至2013年5月陕西核工业215医院血液透析中心确诊慢性肾衰且中医诊断为脾肾气虚证接受血液透析患者146例，根据患者透析编号随机分为两组，对照组74例接受常规血液透析及药物治疗，治疗组72例在对照组治疗基础上加服健脾补肾方。并分别于治疗前、治疗后6个月采用改良主观全面营养评价（SGAN）法、人体测量指标、生化及实验室检测指标等综合评估患者营养状况。结果治疗组治疗后SGAN 评分、体质量指数（BMI）、上臂围（MAC）、肱三头肌皮褶厚度（TSF）、上臂肌围（MAMC）[分别为（9.58±3.15）分、（19.34±0.52）Kg/m2、（27.51±1.95）cm 、（12.92±2.42）mm、（23.64±1.96）cm]均高于对照组[分别为（13.23±3.14）分、（17.29±0.76）Kg/m2、（24.01±2.55）cm、（10.58±2.71）mm、（20.71±2.04）cm，P＜0.05]。治疗后治疗组清白蛋白、前白蛋白、转铁蛋白、血清胆固醇、尿素氮、肌酐水平[分别为（38.19±1.95）g/L、（2.23±0.16）g/L、（0.21±0.04）g/L、（4.02±0.26）mmol/L、（19.58±2.17）mmol/L、（869.54±79.15）mmol/L]均高于对照组[分别为（33.73±1.31）g/L、（1.67±0.25）g/L、（0.17±0.02）g/L、（3.22±0.46）mmol/L、（16.27±1.12）mmol/L、（792.73±71.65）mmol/L]，P＜0.05。结论健脾补肾方可改善脾肾气虚型慢性肾功能衰竭血液透析患者的营养状况，提高其生存质量。
目的：觀察健脾補腎方對脾腎氣虛型慢性腎功能衰竭血液透析患者營養狀況的影響。方法收集2012年6月至2013年5月陝西覈工業215醫院血液透析中心確診慢性腎衰且中醫診斷為脾腎氣虛證接受血液透析患者146例，根據患者透析編號隨機分為兩組，對照組74例接受常規血液透析及藥物治療，治療組72例在對照組治療基礎上加服健脾補腎方。併分彆于治療前、治療後6箇月採用改良主觀全麵營養評價（SGAN）法、人體測量指標、生化及實驗室檢測指標等綜閤評估患者營養狀況。結果治療組治療後SGAN 評分、體質量指數（BMI）、上臂圍（MAC）、肱三頭肌皮褶厚度（TSF）、上臂肌圍（MAMC）[分彆為（9.58±3.15）分、（19.34±0.52）Kg/m2、（27.51±1.95）cm 、（12.92±2.42）mm、（23.64±1.96）cm]均高于對照組[分彆為（13.23±3.14）分、（17.29±0.76）Kg/m2、（24.01±2.55）cm、（10.58±2.71）mm、（20.71±2.04）cm，P＜0.05]。治療後治療組清白蛋白、前白蛋白、轉鐵蛋白、血清膽固醇、尿素氮、肌酐水平[分彆為（38.19±1.95）g/L、（2.23±0.16）g/L、（0.21±0.04）g/L、（4.02±0.26）mmol/L、（19.58±2.17）mmol/L、（869.54±79.15）mmol/L]均高于對照組[分彆為（33.73±1.31）g/L、（1.67±0.25）g/L、（0.17±0.02）g/L、（3.22±0.46）mmol/L、（16.27±1.12）mmol/L、（792.73±71.65）mmol/L]，P＜0.05。結論健脾補腎方可改善脾腎氣虛型慢性腎功能衰竭血液透析患者的營養狀況，提高其生存質量。
목적：관찰건비보신방대비신기허형만성신공능쇠갈혈액투석환자영양상황적영향。방법수집2012년6월지2013년5월협서핵공업215의원혈액투석중심학진만성신쇠차중의진단위비신기허증접수혈액투석환자146례，근거환자투석편호수궤분위량조，대조조74례접수상규혈액투석급약물치료，치료조72례재대조조치료기출상가복건비보신방。병분별우치료전、치료후6개월채용개량주관전면영양평개（SGAN）법、인체측량지표、생화급실험실검측지표등종합평고환자영양상황。결과치료조치료후SGAN 평분、체질량지수（BMI）、상비위（MAC）、굉삼두기피습후도（TSF）、상비기위（MAMC）[분별위（9.58±3.15）분、（19.34±0.52）Kg/m2、（27.51±1.95）cm 、（12.92±2.42）mm、（23.64±1.96）cm]균고우대조조[분별위（13.23±3.14）분、（17.29±0.76）Kg/m2、（24.01±2.55）cm、（10.58±2.71）mm、（20.71±2.04）cm，P＜0.05]。치료후치료조청백단백、전백단백、전철단백、혈청담고순、뇨소담、기항수평[분별위（38.19±1.95）g/L、（2.23±0.16）g/L、（0.21±0.04）g/L、（4.02±0.26）mmol/L、（19.58±2.17）mmol/L、（869.54±79.15）mmol/L]균고우대조조[분별위（33.73±1.31）g/L、（1.67±0.25）g/L、（0.17±0.02）g/L、（3.22±0.46）mmol/L、（16.27±1.12）mmol/L、（792.73±71.65）mmol/L]，P＜0.05。결론건비보신방가개선비신기허형만성신공능쇠갈혈액투석환자적영양상황，제고기생존질량。
Objective To observe the effect of nutritional status change on hemodialysis patients of chronic renal failure and deficiency of spleen and kidney treated bytraditional Chinese medicine(TCM) of warming kidney and invigorating spleen. Methods In our center, 146 patients who were diagnosed chronic renal failure belonging to deficiency of spleen and kidney in TCM were received hemodialysis between Jun2012 and May2013. All patients were randomly divided into a treatment group (n=72) and a control group (n=74). 74 patients in the control groupreceived conventional hemodialysis and medicine treatment, and 72 patients in treatment group received conventional hemodialysis、medicine treatment and TCM treatment of warming kidney and invigorating spleen. The comprehensive nutritional assessment of all patients were treated by modified SGAN method (MQSGAN), anthropometric, biochemical and laboratory examination before and 6 monthsafter the treatment. Results The treatment group patients of modified SGAN(9.58±3.15), BMI (body mass index 19.34±0.52) Kg/m2, MAC(upper arm circumference 27.51±1.95)cm, TSF(tricepsskinfold thickness 12.92± 2.42) mm and MAMC(upper arm muscle circumference 23.64±1.96)cm were significantly improved compared with the control g roup(respectively data 13.23±3.14, 17.29±0.76) Kg/m2, (24.01±2.55, 10.58±2.71) mm, (20.71±2.04)cm, P<0.05,and treatment group patients with ALB(serum albumin 38.19±1.95)g/L, PA(prealbumin 2.23±0.16)g/L, TF(transferrin 0.21±0.04)g/L, CH(cholesterol 4.02±0.26)mmol/L, BUN(blood urea nitrogen 19.58±2.17)mmol/L and SCr (creatinine 869.54±79.15)mmol/L were significant improved also compared with the control group(respectively data 33.73±1.31)g/L, (1.67±0.25)g/L, (0.17±0.02)g/L, (3.22± 0.46)mmol/L, (16.27±1.12)mmol/L, (792.73±71.65)mmol/L, P<0.05. Conclusion Traditional Chinese medicine of warming kidney and invigorating spleen can improve the nutritional status and quality of life on patients with chronic renal failure belonging to deficiency of spleen and kidney type during hemodialysis.
