CAJ | 학술논문

目的：探讨经皮肝穿刺胆道腔内射频消融（RFA）联合支架植入治疗恶性梗阻性黄疸的安全性和疗效。方法对2例恶性梗阻性黄疸患者在行经皮肝穿刺胆道引流术后，行经皮胆道腔内 RFA 联合支架植入术，观察并发症、疗效及术后50 d 支架通畅情况。结果2例患者均成功接受手术治疗，技术成功率100%。均行分段 RFA，术后血清总胆红素水平显著下降。均无胆道出血、胆管穿孔、胆漏等严重并发症发生，随访50 d 月支架通畅。结论经皮肝穿刺胆道腔内射频消融联合支架植入作为恶性梗阻性黄疸介入治疗的新方法，是安全及有效的，但仍需有效的随机对照试验来证实。
목적：탐토경피간천자담도강내사빈소융（RFA）연합지가식입치료악성경조성황달적안전성화료효。방법대2례악성경조성황달환자재행경피간천자담도인류술후，행경피담도강내 RFA 연합지가식입술，관찰병발증、료효급술후50 d 지가통창정황。결과2례환자균성공접수수술치료，기술성공솔100%。균행분단 RFA，술후혈청총담홍소수평현저하강。균무담도출혈、담관천공、담루등엄중병발증발생，수방50 d 월지가통창。결론경피간천자담도강내사빈소융연합지가식입작위악성경조성황달개입치료적신방법，시안전급유효적，단잉수유효적수궤대조시험래증실。
Objective To evaluate the safety and efficacy of percutaneous endobiliary radiofrequency ablation combined with biliary stenting in treating malignant obstructive jaundice. Methods Percutaneous endobiliary radiofrequency ablation combined with biliary stenting was carried out in 2 patients with malignant obstructive jaundice after they received percutaneous transhepatic biliary drainage. The curative effect, complications and stent patency at 50 days after the treatment were recorded. The results were analyzed. Results Successful endobiliary radiofrequency ablation and intraluminal stent implantation was accomplished in both patients, with a technical success rate of 100%. Segmental radiofrequency ablation procedure was employed. After the treatment the serum total bilirubin level was significantly decreased. No bile duct bleeding, perforation of bile duct, bile leakage or other serious complications occurred. The stent remained unobstructed during the follow - up period of 50 days. Conclusion As a new treatment for malignant obstructive jaundice, percutaneous endobiliary radiofrequency ablation combined with biliary stenting is clinically safe and effective, although its long - term efficacy needs to be further proved with randomized controlled trials.