国际中医中药杂志
國際中醫中藥雜誌
국제중의중약잡지
INTERNATIONAL JOURNAL OF TRIDITIONAL CHINESE MEDICINE
2014年
7期
617-619
,共3页
穴位埋线%慢传输型便秘%结肠传输功能%血浆P物质%血管活性肠肽
穴位埋線%慢傳輸型便祕%結腸傳輸功能%血漿P物質%血管活性腸肽
혈위매선%만전수형편비%결장전수공능%혈장P물질%혈관활성장태
Acupuncture point embedding therapy%Slow transit constipation%Colon transmission function%SP%VIP
目的:观察穴位埋线疗法对慢传输型便秘(STC)患者临床疗效及其对结肠传输功能、血浆P物质(SP)、血管活性肠肽(VIP)的影响。方法收集2012年3月至2013年1月青岛市黄岛中医院、青岛市海慈医疗集团、青岛大学医学院附属医院的STC患者128例,采用随机数表法将患者随机分为两组各64例。治疗组采用穴位埋线治疗,对照组口服乳果糖口服液治疗,疗程均为4周。观察两组患者治疗前后的临床疗效及对结肠传输功能、SP、VIP 的影响。结果治疗组治疗前便秘评分量表(CCS)评分为(13.52±3.93)分、治疗后为(8.15±3.77)分;对照组治疗前为(14.11±4.24)分、治疗后为(9.01±2.93)分,两组治疗后 CCS 评分均较同组治疗前降低(P<0.01),但组间比较差异无统计学意义(P>0.05)。治疗后两组血浆SP、VIP水平[治疗组分别为(46.73±1.50)ng/L、(206.10±12.14)ng/L,对照组分别为(40.92±6.25)ng/L、(214.73±7.62)ng/L]均较同组治疗前[治疗组分别为(26.66±0.88)ng/L、(332.68±17.84)ng/L,对照组分别为(23.32±1.75)ng/L、(306.22±20.01)ng/L]改善,差异有统计学意义(P<0.05),且两组比较,血浆SP、VIP水平差异均有统计学意义(P<0.05)。结论穴位埋线疗法可改善STC患者的临床症状及结肠传输功能,并可能通过调节血SP、VIP水平达到治疗效果。
目的:觀察穴位埋線療法對慢傳輸型便祕(STC)患者臨床療效及其對結腸傳輸功能、血漿P物質(SP)、血管活性腸肽(VIP)的影響。方法收集2012年3月至2013年1月青島市黃島中醫院、青島市海慈醫療集糰、青島大學醫學院附屬醫院的STC患者128例,採用隨機數錶法將患者隨機分為兩組各64例。治療組採用穴位埋線治療,對照組口服乳果糖口服液治療,療程均為4週。觀察兩組患者治療前後的臨床療效及對結腸傳輸功能、SP、VIP 的影響。結果治療組治療前便祕評分量錶(CCS)評分為(13.52±3.93)分、治療後為(8.15±3.77)分;對照組治療前為(14.11±4.24)分、治療後為(9.01±2.93)分,兩組治療後 CCS 評分均較同組治療前降低(P<0.01),但組間比較差異無統計學意義(P>0.05)。治療後兩組血漿SP、VIP水平[治療組分彆為(46.73±1.50)ng/L、(206.10±12.14)ng/L,對照組分彆為(40.92±6.25)ng/L、(214.73±7.62)ng/L]均較同組治療前[治療組分彆為(26.66±0.88)ng/L、(332.68±17.84)ng/L,對照組分彆為(23.32±1.75)ng/L、(306.22±20.01)ng/L]改善,差異有統計學意義(P<0.05),且兩組比較,血漿SP、VIP水平差異均有統計學意義(P<0.05)。結論穴位埋線療法可改善STC患者的臨床癥狀及結腸傳輸功能,併可能通過調節血SP、VIP水平達到治療效果。
목적:관찰혈위매선요법대만전수형편비(STC)환자림상료효급기대결장전수공능、혈장P물질(SP)、혈관활성장태(VIP)적영향。방법수집2012년3월지2013년1월청도시황도중의원、청도시해자의료집단、청도대학의학원부속의원적STC환자128례,채용수궤수표법장환자수궤분위량조각64례。치료조채용혈위매선치료,대조조구복유과당구복액치료,료정균위4주。관찰량조환자치료전후적림상료효급대결장전수공능、SP、VIP 적영향。결과치료조치료전편비평분량표(CCS)평분위(13.52±3.93)분、치료후위(8.15±3.77)분;대조조치료전위(14.11±4.24)분、치료후위(9.01±2.93)분,량조치료후 CCS 평분균교동조치료전강저(P<0.01),단조간비교차이무통계학의의(P>0.05)。치료후량조혈장SP、VIP수평[치료조분별위(46.73±1.50)ng/L、(206.10±12.14)ng/L,대조조분별위(40.92±6.25)ng/L、(214.73±7.62)ng/L]균교동조치료전[치료조분별위(26.66±0.88)ng/L、(332.68±17.84)ng/L,대조조분별위(23.32±1.75)ng/L、(306.22±20.01)ng/L]개선,차이유통계학의의(P<0.05),차량조비교,혈장SP、VIP수평차이균유통계학의의(P<0.05)。결론혈위매선요법가개선STC환자적림상증상급결장전수공능,병가능통과조절혈SP、VIP수평체도치료효과。
Objective To explore the clinical efficacy of acupuncture point embedding therapy in the treatment of slow transit constipation (STC)and the influence on the colon transmission function,plasma substance P(SP), vasoactive intestinal peptide(VIP). Methods A total of 128 slow transit constipation patients were involved in the study and divided randomly into two groups by using stochastic indicator: a treatment group (treated with acupuncture point embedding therapy) and a control group (treated with lactulose oral liquid). The clinical effects, colon transmission function, the influence of SP, and VIP were observed for STC patients. Results In the treatment group, CCS score was (13.52±3.93) before treatment and(8.15±3.77) after the treatment. In the control group CCS score was (14.11±4.24) and (9.01±2.93) respectively before and after the treatment, CCS score in both groups showed significantly improvement after the treatment (P<0.01), and there was no significant difference between groups (P>0.05). The plasma SP and VIP level of the two groups after the treatment [treatment group (46.73±1.50) ng/L,(206.10±12.14) ng/L, the control group(40.92±6.25)ng/L,(214.73± 7.62)ng/L] were also improved than before [treatment group was(26.66±0.88)ng/L, (332.68±17.84)ng/L, the control group was (23.32±1.75)ng/L,(306.22±20.01)ng/L], with statistically significant(P<0.05), and the difference between the two groups were also significant(P<0.05).Conclusion The acupuncture point embedding therapy is effective for STC, and it can regulate the level of SP and VIP.