国际中医中药杂志
國際中醫中藥雜誌
국제중의중약잡지
INTERNATIONAL JOURNAL OF TRIDITIONAL CHINESE MEDICINE
2014年
4期
318-320
,共3页
芍药甘草汤%三叉神经痛%原发性
芍藥甘草湯%三扠神經痛%原髮性
작약감초탕%삼차신경통%원발성
Shaoyao-Gancao decoction%Trigeminal neuralgia%Primary
目的：观察芍药甘草汤加减联合卡马西平治疗原发性三叉神经痛的临床疗效。方法将76例原发性三叉神经痛患者采用简单随机化分组法随机分为两组各38例。治疗组给予芍药甘草汤联合卡马西平治疗，对照组接受卡马西平治疗。观察两组治疗后及随访第6周临床疗效、疼痛改善情况及不良反应。结果治疗后治疗组总有效率为89.3%（34/38）高于对照组的75.5%（28/38），差异有统计学意义（P＝0.043）。两组患者治疗后日发作频率、持续时间、VAS评分等均较同组治疗前明显改善明显[治疗组治疗后分别为(0.54±0.78)次、(2.15±1.73)s、(1.58±1.26)分,随访6周时分别为(0.24±0.63)次、(1.36±1.03)s、(0.86±1.95)分；对照组治疗后分别为(1.98±1.68)次、(3.96±1.49)s、(3.02±1.45)分，随访6周时分别为(1.06±1.78)次、(1.97±1.69)s、(2.13±1.54)分，P＜0.05]，且治疗组疗效优于对照组（P＜0.05）。结论芍药甘草汤联合卡马西平治疗原发性三叉神经痛有较好的临床疗效。
目的：觀察芍藥甘草湯加減聯閤卡馬西平治療原髮性三扠神經痛的臨床療效。方法將76例原髮性三扠神經痛患者採用簡單隨機化分組法隨機分為兩組各38例。治療組給予芍藥甘草湯聯閤卡馬西平治療，對照組接受卡馬西平治療。觀察兩組治療後及隨訪第6週臨床療效、疼痛改善情況及不良反應。結果治療後治療組總有效率為89.3%（34/38）高于對照組的75.5%（28/38），差異有統計學意義（P＝0.043）。兩組患者治療後日髮作頻率、持續時間、VAS評分等均較同組治療前明顯改善明顯[治療組治療後分彆為(0.54±0.78)次、(2.15±1.73)s、(1.58±1.26)分,隨訪6週時分彆為(0.24±0.63)次、(1.36±1.03)s、(0.86±1.95)分；對照組治療後分彆為(1.98±1.68)次、(3.96±1.49)s、(3.02±1.45)分，隨訪6週時分彆為(1.06±1.78)次、(1.97±1.69)s、(2.13±1.54)分，P＜0.05]，且治療組療效優于對照組（P＜0.05）。結論芍藥甘草湯聯閤卡馬西平治療原髮性三扠神經痛有較好的臨床療效。
목적：관찰작약감초탕가감연합잡마서평치료원발성삼차신경통적림상료효。방법장76례원발성삼차신경통환자채용간단수궤화분조법수궤분위량조각38례。치료조급여작약감초탕연합잡마서평치료，대조조접수잡마서평치료。관찰량조치료후급수방제6주림상료효、동통개선정황급불량반응。결과치료후치료조총유효솔위89.3%（34/38）고우대조조적75.5%（28/38），차이유통계학의의（P＝0.043）。량조환자치료후일발작빈솔、지속시간、VAS평분등균교동조치료전명현개선명현[치료조치료후분별위(0.54±0.78)차、(2.15±1.73)s、(1.58±1.26)분,수방6주시분별위(0.24±0.63)차、(1.36±1.03)s、(0.86±1.95)분；대조조치료후분별위(1.98±1.68)차、(3.96±1.49)s、(3.02±1.45)분，수방6주시분별위(1.06±1.78)차、(1.97±1.69)s、(2.13±1.54)분，P＜0.05]，차치료조료효우우대조조（P＜0.05）。결론작약감초탕연합잡마서평치료원발성삼차신경통유교호적림상료효。
Objective To Observe the effects of treating primary trigeminal neuralgia with modified Shaoyao-Gancao decoction and carbamazepine. Methods 76 patients with primary trigeminal neuralgia were randomly divided into a treatment group and a control group, 38 patients in each. The treatment group was treated with modified Shaoyao-Gancao decoction and carbamazepine; and the control group was treated with carbamazepine only. Clinical curative effect, pain improvements and adverse reactions were observed after the treatment and 6 week follow-up. Results The total effective rate was 89.3%and 75.5%in the treatment group and the control group respectively, the difference was statistically significant(P=0.043). The onset frequency, duration, degree of pain were all improved in both groups after the treatment and 6 week follow-up[treatment group after the treatment is (0.54±0.78), (2.15±1.73), (1.58±1.26), 6 week follow-up is (0.24±0.63), (1.36±1.03),0.86±1.95);control group after the treatment is (1.98±1.68), (3.96±1.49), (3.02±1.45), 6 week follow-up is (1.06±1.78), (1.97±1.69), (2.13±1.54), P<0.05],and the treatment group was better than the control group(P=0.040 and 0.039 respectively). Conclusion Modified Shaoyao-Gancao decoction combined carbamazepine has good clinical curative effect in treating primary trigeminal neuralgia.
