国际中医中药杂志
國際中醫中藥雜誌
국제중의중약잡지
INTERNATIONAL JOURNAL OF TRIDITIONAL CHINESE MEDICINE
2014年
4期
307-310
,共4页
良性原发性眼睑痉挛%针刺%A型肉毒素%疗效评价
良性原髮性眼瞼痙攣%針刺%A型肉毒素%療效評價
량성원발성안검경련%침자%A형육독소%료효평개
Benign primary blepharospasm%Acupuncture%Botulinum toxin type A%Evaluation of effect
目的：在健脾疏肝理论的指导下，观察针刺治疗良性原发性眼睑痉挛（benign primary blepharospasm，BPB）患者的临床疗效。方法选择2012年1月至2013年7月北京同仁医院眼科门诊BPB患者为研究对象，按随机数字表法将患者随机分为两组各40例。治疗组采用健脾疏肝法针刺取穴治疗，对照组在眼周注射A型肉毒素治疗。治疗结束后比较两组有效率、视功能损害生存质量评分、抑郁自评量表（汉密顿量表）评分。结果治疗组总有效率为95%（38/40），高于对照组的72.5%（29/40），两组总有效率比较，差异有统计学意义（P＝0.006）；两组视功能损害生存质量量表评分比较，治疗前比较差异无统计学意义[治疗组为（121.88±30.16）分，对照组为（121.00±28.72）分，P＞0.05]，治疗后比较差异有统计学意义[治疗组为（70.00±22.88）分，对照组为（95.25±28.39）分，P＜0.01]；两组抑郁自评量表（汉密顿量表）评分比较，治疗前比较差异无统计学意义[治疗组为（15.90±7.99）分，对照组为（15.75±6.26）分，P＞0.05]，治疗后比较差异有统计学意义[治疗组为（10.40±4.95），对照组为（13.38±6.32）分，P＜0.01]。结论健脾疏肝针刺法治疗BPB疗效优于注射A型肉毒素，同时具有保护视功能和防治抑郁的作用。
目的：在健脾疏肝理論的指導下，觀察針刺治療良性原髮性眼瞼痙攣（benign primary blepharospasm，BPB）患者的臨床療效。方法選擇2012年1月至2013年7月北京同仁醫院眼科門診BPB患者為研究對象，按隨機數字錶法將患者隨機分為兩組各40例。治療組採用健脾疏肝法針刺取穴治療，對照組在眼週註射A型肉毒素治療。治療結束後比較兩組有效率、視功能損害生存質量評分、抑鬱自評量錶（漢密頓量錶）評分。結果治療組總有效率為95%（38/40），高于對照組的72.5%（29/40），兩組總有效率比較，差異有統計學意義（P＝0.006）；兩組視功能損害生存質量量錶評分比較，治療前比較差異無統計學意義[治療組為（121.88±30.16）分，對照組為（121.00±28.72）分，P＞0.05]，治療後比較差異有統計學意義[治療組為（70.00±22.88）分，對照組為（95.25±28.39）分，P＜0.01]；兩組抑鬱自評量錶（漢密頓量錶）評分比較，治療前比較差異無統計學意義[治療組為（15.90±7.99）分，對照組為（15.75±6.26）分，P＞0.05]，治療後比較差異有統計學意義[治療組為（10.40±4.95），對照組為（13.38±6.32）分，P＜0.01]。結論健脾疏肝針刺法治療BPB療效優于註射A型肉毒素，同時具有保護視功能和防治抑鬱的作用。
목적：재건비소간이론적지도하，관찰침자치료량성원발성안검경련（benign primary blepharospasm，BPB）환자적림상료효。방법선택2012년1월지2013년7월북경동인의원안과문진BPB환자위연구대상，안수궤수자표법장환자수궤분위량조각40례。치료조채용건비소간법침자취혈치료，대조조재안주주사A형육독소치료。치료결속후비교량조유효솔、시공능손해생존질량평분、억욱자평량표（한밀돈량표）평분。결과치료조총유효솔위95%（38/40），고우대조조적72.5%（29/40），량조총유효솔비교，차이유통계학의의（P＝0.006）；량조시공능손해생존질량량표평분비교，치료전비교차이무통계학의의[치료조위（121.88±30.16）분，대조조위（121.00±28.72）분，P＞0.05]，치료후비교차이유통계학의의[치료조위（70.00±22.88）분，대조조위（95.25±28.39）분，P＜0.01]；량조억욱자평량표（한밀돈량표）평분비교，치료전비교차이무통계학의의[치료조위（15.90±7.99）분，대조조위（15.75±6.26）분，P＞0.05]，치료후비교차이유통계학의의[치료조위（10.40±4.95），대조조위（13.38±6.32）분，P＜0.01]。결론건비소간침자법치료BPB료효우우주사A형육독소，동시구유보호시공능화방치억욱적작용。
Objective To observe and compare the clinical effect of treating benign primary blepharospasm(BPB)with acupuncture and injection of type A botulinum toxin. Methods Between January 2012 to July 2013, 80 cases of BPB patients in ophthalmology of Tongren hospital were randomly recruited into a acupuncture group and a control group, with 40 cases in either group. The acupuncture group was treated with acupuncture on points of strengthening spleen and distributing liver and the control group was treated by type A botulinum toxin injection around effected eyes. Then effective rate, visual impairment of quality of life scale and self-rating depressive scale were tested after the treatments. Results The total effective rate of acupuncture was 95%, which was better than injection with type A botulinum toxin, with statistical difference(P<0.01). There was no statistical difference in visual impairment of quality of life scale in both groups after the treatment compared with before treatment(P>0.05). Visual impairment score was (121.88±30.16) and (121.00±28.72) in the acupuncture group and control group respectively before the treatment, However, acupuncture group(70.00±22.88)reduced less than control group(95.25±28.39)after the treatment, and there was statistical difference(P<0.01). There was no statistical difference in self-rating depressive scale in groups before treatments(P>0.05), (acupuncture group was(15.90±7.99) and control group was(15.75±6.26). However, acupuncture group(10.40±4.95)reduced less than control group(13.38±6.32)after the treatment, and there was statistical difference(P<0.01). Conclusion It proved that the therapy of acupuncture with strengthening spleen and distributing liver method for benign primary blepharospasm has a better result than injection with type A Botulinum toxin. Moreover, acupuncture can promote optical function and prevent depression for BPB patients.
