CAJ | 학술논문

目的：探讨两种部分脾栓塞方法（PSE）治疗肝硬化门脉高压症的临床疗效及统计学差异。方法62例肝硬化并发门脉高压及脾功能亢进患者分作外周栓塞组和下极栓塞组，两组分别行PSE。对比两组术前、术后彩色多普勒超声，分别检测患者门静脉和脾静脉内径、血流速度及血流量，脾脏长径、厚度。结果栓塞面积60%~80%者52例，>80%者10例。术后患者门静脉主干及脾静脉血流速度和血流量均较术前降低；脾脏长径和厚度两组均较术前变小，两组相比差异有统计学意义（P<0.05）；结论通过PSE能有效地缓解肝硬化患者的门脉高压，同时选择性外周动脉栓塞对门脉压力的减低比脾脏下极栓塞更为明显。
목적：탐토량충부분비전새방법（PSE）치료간경화문맥고압증적림상료효급통계학차이。방법62례간경화병발문맥고압급비공능항진환자분작외주전새조화하겁전새조，량조분별행PSE。대비량조술전、술후채색다보륵초성，분별검측환자문정맥화비정맥내경、혈류속도급혈류량，비장장경、후도。결과전새면적60%~80%자52례，>80%자10례。술후환자문정맥주간급비정맥혈류속도화혈류량균교술전강저；비장장경화후도량조균교술전변소，량조상비차이유통계학의의（P<0.05）；결론통과PSE능유효지완해간경화환자적문맥고압，동시선택성외주동맥전새대문맥압력적감저비비장하겁전새경위명현。
Objective To investigate the clinical effects of two different partial splenic embolization (PSE) methods in treating portal hypertension due to cirrhosis, and to statistically analyze the difference between the two PSE methods. Methods Sixty-two patients with cirrhotic portal hypertension complicated by hypersplenism were divided into group A (peripheral embolization group) and Group B (lower- pole embolization group). Partial splenic embolization with sponge was carried out in all patients of both groups. Before and after PSE color Doppler ultrasoundgraphy was performed to determine the inner diameter of the portal vein and splenic vein, the velocity and rate of flow, the length and thickness of spleen, etc. The results were compared between the two groups. Results The splenic embolization area within 60% - 80%was obtained in 42 patients, and the embolization area>80%was seen in 20 patients. After PSE, decreased flow velocity as well as flow rate was detected in all patients, and both the length and thickness of the spleen were also significantly reduced when compared with the data determined before PSE. The differences between the two groups were statistically significantly (P < 0.05). Conclusion Partial splenic embolization can effectively relieve the portal hypertension caused by cirrhosis, and selective peripheral arterial embolization is superior to splenic lower-pole embolization in decreasing the portal pressure.