CAJ | 학술논문

2014年2月暴发于西非地区的埃博拉出血热是历史上最严重的一次疫情，药物和疫苗的研究开发受到特别关注。该研究利用Thomson Reuters （汤森路透）的Cortellis数据库和既往研究积累对埃博拉出血热药物和疫苗研究开发整体态势进行分析，为正确把握开发情况提供参考。研究结果显示，疫苗、中和抗体、小分子抗病毒药物、RNA干扰技术药物和核苷酸是抗埃博拉病毒的5个重要类别，每个类别都有前景看好的品种，值得继续跟踪和关注。
2014년2월폭발우서비지구적애박랍출혈열시역사상최엄중적일차역정，약물화역묘적연구개발수도특별관주。해연구이용Thomson Reuters （탕삼로투）적Cortellis수거고화기왕연구적루대애박랍출혈열약물화역묘연구개발정체태세진행분석，위정학파악개발정황제공삼고。연구결과현시，역묘、중화항체、소분자항병독약물、RNA간우기술약물화핵감산시항애박랍병독적5개중요유별，매개유별도유전경간호적품충，치득계속근종화관주。
The outbreak of Ebola hemorrhagic fever in West Africa in February 2014 is the worst one in the history of the disease.Medicines and vaccines for Ebola have attracted special attention .This study utilizes Cortellis database of Thom-son Reuters and knowledge about Ebola virus to analyze current R&D of medicines and vaccines for Ebola in order to offer references for research and development .Study findings shows that there are mainly 5 important categories:vaccines, neu-tralizing antibodies , small-molecule anti-Ebola drugs , RNAi drugs and nucleotide drugs .In each category , there are prom-ising products under development that are worthy of attention .