CAJ | 학술논문

目的：探讨不孕患者子宫内膜病变的病理类型以及对治疗效果的影响。方法：选取不孕患者104例，于月经来潮后12h内行诊断性刮宫并进行病理分析。分泌反应类患者给予活血补肾为主的中医治疗，增生反应类患者给予克罗米芬口服。结果：子宫内膜病变中以分泌类反应较多，其中尤其以分泌欠佳所占比例最大，而增生类反应中以增生反应较多见。不同程度分泌异常患者随着病变严重程度增加，治疗效果也越来越差，组间比较差异明显，具有统计学意义（P＜0.05）。不同类型增生异常患者治疗效果差别不大，无统计学意义（P＞0.05）。结论：分泌类反应患者的病理诊断有助于对患者预后作出判断；增生类反应者虽然不同类型预后差别不大，但是治疗手段却不同，因此病理诊断也十分必要。
목적：탐토불잉환자자궁내막병변적병리류형이급대치료효과적영향。방법：선취불잉환자104례，우월경래조후12h내행진단성괄궁병진행병리분석。분비반응류환자급여활혈보신위주적중의치료，증생반응류환자급여극라미분구복。결과：자궁내막병변중이분비류반응교다，기중우기이분비흠가소점비례최대，이증생류반응중이증생반응교다견。불동정도분비이상환자수착병변엄중정도증가，치료효과야월래월차，조간비교차이명현，구유통계학의의（P＜0.05）。불동류형증생이상환자치료효과차별불대，무통계학의의（P＞0.05）。결론：분비류반응환자적병리진단유조우대환자예후작출판단；증생류반응자수연불동류형예후차별불대，단시치료수단각불동，인차병리진단야십분필요。
Objectives:To investigate the pathological type of infertility patients with endometrial lesions and their impact on the treatment effect.Methods:1 04 infertile patients were selected and applied diagnostic curet-tage within 1 2h since the beginning of menstrual period for pathological analysis.Patients in the secretory reaction class received Chinese medicine treatment highlighting Huoxue tonifying the kidney;patients in the proliferative re-sponse class were given oral clomiphene citrate.Results:Of the endometrial lesions,secretion response took the majority,especially poor secretion;while for the proliferation class,proliferative reaction was the majority.With the increasing severity degrees of diacrisis,treatment effect was getting worse and worse,with statistically significant differences between groups (P<0.05 ).For patients with different types of abnormal hyperplasia,treatment effect was not very different with no statistical significance (P>0.05).Conclusion:The pathological diagnosis of patients in the secretory response class is helpful to judge the prognosis;while for patients with proliferative response;al-though prognostic difference is not significant,treatment methods are different,so it is very necessary for pathologi-cal diagnosis.