中医临床研究
中醫臨床研究
중의림상연구
CLINICAL JOURNAL OF CHINESE MEDICINE
2014年
25期
90-91
,共2页
复发性口腔溃疡%滋阴清热口服液%左旋咪唑片
複髮性口腔潰瘍%滋陰清熱口服液%左鏇咪唑片
복발성구강궤양%자음청열구복액%좌선미서편
Recurrent oral ulcers%The Ziyin Qingre oral liquid%Levamisole tablets
目的：了解滋阴清热口服液治疗复发性口腔溃疡临床价值。方法：将360例患者随机分两组，治疗组用自拟滋阴清热口服液（石斛，生地，青黛，紫草，泽漆，旱莲草，竹叶，滑石，砂仁，肉桂，金荞麦，甘草，10mL/次，3次/d口服）治疗，对照组用左旋咪唑片、复合维生素B等，两组均以2周为1个疗程，共治疗2个疗程。近期疗效按：①显效：平均溃疡期缩短，疼痛指数减少；②有效：平均溃疡期缩短而疼痛指数无改变，或平均溃疡期未缩短而疼痛指数减少；③无效：未达到有效标准。远期按：①痊愈：终止复发1年以上，各种伴随症状完全消失；②显效：总间歇时间延长且溃疡数减少；③有效：总间歇时间延长但溃疡数无变化，或总间歇时间无变化，但溃疡数减少；④无效：未达到效标准。结果：治疗组的局部治疗效果有效率为79.58%，远期治疗效果有效率为90.42%；治疗组与对照组局部治疗效果差别存在统计学意义（μ＝4.823，P＝0.030）；治疗组与对照组远期治疗效果差别存在统计学意义（μ＝4.026， P＝0.000）。结论：自拟滋阴清热口服液治疗复发性口腔溃疡疗效可靠，服用方便，且价格低廉。
目的：瞭解滋陰清熱口服液治療複髮性口腔潰瘍臨床價值。方法：將360例患者隨機分兩組，治療組用自擬滋陰清熱口服液（石斛，生地，青黛，紫草，澤漆，旱蓮草，竹葉，滑石，砂仁，肉桂，金蕎麥，甘草，10mL/次，3次/d口服）治療，對照組用左鏇咪唑片、複閤維生素B等，兩組均以2週為1箇療程，共治療2箇療程。近期療效按：①顯效：平均潰瘍期縮短，疼痛指數減少；②有效：平均潰瘍期縮短而疼痛指數無改變，或平均潰瘍期未縮短而疼痛指數減少；③無效：未達到有效標準。遠期按：①痊愈：終止複髮1年以上，各種伴隨癥狀完全消失；②顯效：總間歇時間延長且潰瘍數減少；③有效：總間歇時間延長但潰瘍數無變化，或總間歇時間無變化，但潰瘍數減少；④無效：未達到效標準。結果：治療組的跼部治療效果有效率為79.58%，遠期治療效果有效率為90.42%；治療組與對照組跼部治療效果差彆存在統計學意義（μ＝4.823，P＝0.030）；治療組與對照組遠期治療效果差彆存在統計學意義（μ＝4.026， P＝0.000）。結論：自擬滋陰清熱口服液治療複髮性口腔潰瘍療效可靠，服用方便，且價格低廉。
목적：료해자음청열구복액치료복발성구강궤양림상개치。방법：장360례환자수궤분량조，치료조용자의자음청열구복액（석곡，생지，청대，자초，택칠，한련초，죽협，활석，사인，육계，금교맥，감초，10mL/차，3차/d구복）치료，대조조용좌선미서편、복합유생소B등，량조균이2주위1개료정，공치료2개료정。근기료효안：①현효：평균궤양기축단，동통지수감소；②유효：평균궤양기축단이동통지수무개변，혹평균궤양기미축단이동통지수감소；③무효：미체도유효표준。원기안：①전유：종지복발1년이상，각충반수증상완전소실；②현효：총간헐시간연장차궤양수감소；③유효：총간헐시간연장단궤양수무변화，혹총간헐시간무변화，단궤양수감소；④무효：미체도효표준。결과：치료조적국부치료효과유효솔위79.58%，원기치료효과유효솔위90.42%；치료조여대조조국부치료효과차별존재통계학의의（μ＝4.823，P＝0.030）；치료조여대조조원기치료효과차별존재통계학의의（μ＝4.026， P＝0.000）。결론：자의자음청열구복액치료복발성구강궤양료효가고，복용방편，차개격저렴。
Objective: To observe clinical value of the Ziyin Qingre oral liquid on recurrent oral ulcers. Methods: 360 patients were randomly divided into two groups, the treatment group was treated with the Ziyin Qingre oral liquid, 10mL every time, 3 times a day; the control group was given levamisole tablets, vitamin B. 2 weeks for 1 course, with 2 courses of treatment. Recent efficacy: i. Markedly effective: Shortened average period of ulcer and decreased pain index; ii. Effective: Shortened average period of ulcer and no changes for pain index, or decreased pain index and no changes for average period of ulcer; iii. Invalid: Not meet the effective standards. Long-term efficacy: i. Cure: Without relapse more than 1 year, accompanied symptoms disappearing; ii. Markedly effective: Prolonged intermittent time and decreased ulcers; iii. Effective: Prolonged intermittent time and no changes for ulcer, or decreased ulcers and no change for intermittent time; iv. Invalid: Not meet the effective standards. Results: In the treatment, the local treatment efficacy was 79.58%, long-term treatment efficacy was 90.42%. The difference of the local treatment efficacy was statistically significant (μ=4.823,P=0.030); there is statistical significance in the long-term treatment efficacy between the two groups (μ=4.026,P=0.000). Conclusion: The Ziyin Qingre oral liquid was confirmed with good effects, and was easy in take, and low price.
