中医临床研究
中醫臨床研究
중의림상연구
CLINICAL JOURNAL OF CHINESE MEDICINE
2014年
25期
45-46
,共2页
小儿频复发性肾病%中医证型%病理类型%相关性分析
小兒頻複髮性腎病%中醫證型%病理類型%相關性分析
소인빈복발성신병%중의증형%병리류형%상관성분석
Frequently relapsing nephrotic syndrome in children%TCM syndrome%Pathological types%Relativity analysis
目的：探讨小儿频复发性肾病（FRNS）中医证型同病理类型之间的相关性。方法：随机选取我院2010年7月-2013年11月期间收治的诊断为FRNS的患儿50例，对其进行病理诊断和中西辨证分型，并对治疗前后患儿的血生化、尿常规、肾功能检查结果进行对比分析。结果：诊断结果表明，中医辨证分型主要为脾肾阳虚、肝肾阴虚，其次为肾虚血瘀、湿热内蕴等；病理类型主要为弥漫系膜增生性肾小球炎（MsPGN）、局灶节段性肾小球硬化＋系膜增生性肾炎（FSGS＋MsPGN）及IgA肾病。其中肝肾阴虚患者中多为MsPGN，湿热内蕴型患者中多为IgAN，呈正相关关系。结论：临床上可以将IgAN和MsPGN作为湿热内蕴型和肝肾阴虚型的辨证依据和客观指标，用以指导临床治疗。
目的：探討小兒頻複髮性腎病（FRNS）中醫證型同病理類型之間的相關性。方法：隨機選取我院2010年7月-2013年11月期間收治的診斷為FRNS的患兒50例，對其進行病理診斷和中西辨證分型，併對治療前後患兒的血生化、尿常規、腎功能檢查結果進行對比分析。結果：診斷結果錶明，中醫辨證分型主要為脾腎暘虛、肝腎陰虛，其次為腎虛血瘀、濕熱內蘊等；病理類型主要為瀰漫繫膜增生性腎小毬炎（MsPGN）、跼竈節段性腎小毬硬化＋繫膜增生性腎炎（FSGS＋MsPGN）及IgA腎病。其中肝腎陰虛患者中多為MsPGN，濕熱內蘊型患者中多為IgAN，呈正相關關繫。結論：臨床上可以將IgAN和MsPGN作為濕熱內蘊型和肝腎陰虛型的辨證依據和客觀指標，用以指導臨床治療。
목적：탐토소인빈복발성신병（FRNS）중의증형동병리류형지간적상관성。방법：수궤선취아원2010년7월-2013년11월기간수치적진단위FRNS적환인50례，대기진행병리진단화중서변증분형，병대치료전후환인적혈생화、뇨상규、신공능검사결과진행대비분석。결과：진단결과표명，중의변증분형주요위비신양허、간신음허，기차위신허혈어、습열내온등；병리류형주요위미만계막증생성신소구염（MsPGN）、국조절단성신소구경화＋계막증생성신염（FSGS＋MsPGN）급IgA신병。기중간신음허환자중다위MsPGN，습열내온형환자중다위IgAN，정정상관관계。결론：림상상가이장IgAN화MsPGN작위습열내온형화간신음허형적변증의거화객관지표，용이지도림상치료。
Objective: To explore relativity between TCM syndromes and pathological types in children with frequently relapsing nephrotic syndrome (FRNS). Methods: 50 children with FRNS admitted from July 2010 to November 2013 were selected randomly. The 50 children were detected and classified by syndrome differentiation; examining results of blood biochemistry, urine routine and renal function were recorded before and after treatment. Results: TCM syndrome differentiation mainly included Pishen Yangxu, Ganshen Yinxu, the sequence was Shenxu Xueyu, Shire Neiyun. Pathological types mainly included MsPGN, FSGS+MsPGN andIgAN. Patients withGanshen Yinxu inclined to MsPGN,patients with Shire Neiyun inclined toIgAN. TCM syndromeswere positively correlated withpathological types. Conclusion: IgAN and MsPGN could be dialectical basis and objective indicators of Shire Neiyun and Ganshen Yinxu in clinical work to guide clinical treatment.
