中医临床研究
中醫臨床研究
중의림상연구
CLINICAL JOURNAL OF CHINESE MEDICINE
2014年
25期
4-6
,共3页
脑转移瘤%鸦胆子油乳注射液%替莫唑胺
腦轉移瘤%鴉膽子油乳註射液%替莫唑胺
뇌전이류%아담자유유주사액%체막서알
Brain metastases%Javanica oil emulsion injection%Temozolomide
目的：观察鸦胆子油乳注射液联合替莫唑胺治疗脑转移瘤的疗效并进行分析。方法：41例患者随机分成观察组（21例）和对照组（20例）。观察组应用替莫唑胺加鸦胆子油乳注射液，并予支持治疗；对照组予最佳对症支持治疗。结果：观察组缓解率47.61%，对照组缓解率25.00%，两组差异有统计学意义（P<0.05）。观察组治疗后在临床症状、体征，生存质量及生存期方面均优于对照组，两组比较，差异有统计学意义（P<0.05）。结论：替莫唑胺联合鸦胆子油乳剂治疗脑转移瘤可提高患者的近期临床疗效，改善生存质量，延长生存期。
目的：觀察鴉膽子油乳註射液聯閤替莫唑胺治療腦轉移瘤的療效併進行分析。方法：41例患者隨機分成觀察組（21例）和對照組（20例）。觀察組應用替莫唑胺加鴉膽子油乳註射液，併予支持治療；對照組予最佳對癥支持治療。結果：觀察組緩解率47.61%，對照組緩解率25.00%，兩組差異有統計學意義（P<0.05）。觀察組治療後在臨床癥狀、體徵，生存質量及生存期方麵均優于對照組，兩組比較，差異有統計學意義（P<0.05）。結論：替莫唑胺聯閤鴉膽子油乳劑治療腦轉移瘤可提高患者的近期臨床療效，改善生存質量，延長生存期。
목적：관찰아담자유유주사액연합체막서알치료뇌전이류적료효병진행분석。방법：41례환자수궤분성관찰조（21례）화대조조（20례）。관찰조응용체막서알가아담자유유주사액，병여지지치료；대조조여최가대증지지치료。결과：관찰조완해솔47.61%，대조조완해솔25.00%，량조차이유통계학의의（P<0.05）。관찰조치료후재림상증상、체정，생존질량급생존기방면균우우대조조，량조비교，차이유통계학의의（P<0.05）。결론：체막서알연합아담자유유제치료뇌전이류가제고환자적근기림상료효，개선생존질량，연장생존기。
Objective: To observe and analyze the clinical efficacy of javanica oil emulsion plus temozolomide on brain metastases. Methods: 41 patients were randomly divided into the observationgroup (n=21) and the control group (n=20), the observation group was given javanica oil emulsion plus temozolomide and supportive treatment, while the control group was given symptomatic and supportive treatment. Results: The total efficiency in the observation group (47.61%) was significantly better than that (25.00%) in the control (P<0.05). Clinical symptoms, sign, survival quality and time in the observation group was better than those in the control group (P<0.05). Conclusion: Javanica oil emulsion plus temozolomide can improve clinical effects and life quality, and lengthen survival time.
