CAJ | 학술논문

目的：探讨联合抗栓治疗对心肌梗死患者血清IL-6、TNF-α、CPR水平的影响。方法选取2011年8月-2013年8月我院收治的100例心肌梗死患者，依据随机数字表法将这些患者分为两组，即观察组（50例）和对照组（50例）。给予对照组患者低分子肝素+阿司匹林治疗，给予观察组患者低分子肝素+阿司匹林+左卡尼汀治疗。结果观察组患者治疗的总有效率90.0%（45/50）明显比对照组72.0%（36/50）高（P<0.05），血清IL-6、TNF-α水平均明显比对照组低（P<0.05），CPR水平明显比对照组高（P<0.05）。结论联合抗栓治疗能够有效改善心肌梗死患者的血清IL-6、TNF-α、CPR等炎性指标。
목적：탐토연합항전치료대심기경사환자혈청IL-6、TNF-α、CPR수평적영향。방법선취2011년8월-2013년8월아원수치적100례심기경사환자，의거수궤수자표법장저사환자분위량조，즉관찰조（50례）화대조조（50례）。급여대조조환자저분자간소+아사필림치료，급여관찰조환자저분자간소+아사필림+좌잡니정치료。결과관찰조환자치료적총유효솔90.0%（45/50）명현비대조조72.0%（36/50）고（P<0.05），혈청IL-6、TNF-α수평균명현비대조조저（P<0.05），CPR수평명현비대조조고（P<0.05）。결론연합항전치료능구유효개선심기경사환자적혈청IL-6、TNF-α、CPR등염성지표。
Objective To investigate the impact of combined antithrombotic therapy on serum IL-6, TNF-α, CPR levels of patients with myocardial infarction. Methods 100 cases of myocardial infarction patients in our hospital from August 2011 to August 2013 were selected, these patients were divided into two groups according to the random number table, namely the observation group (50 cases) and control group (50 cases). The control group were given low molecular weight heparin+aspirin therapy, while the obser-vation group were given low molecular weight heparin + aspirin + L-carnitine therapy. Results The total effective treatment of the observation group 90.0% (45/50) was significantly higher than the control group72.0% (36/50)(P<0.05), The serum IL-6, TNF-αlevels of the observation group were significantly lower(P<0.05), the CPR level was significantly higher than the control group (P<0.05). Conclusion The combined antithrombotic therapy can improve the levels of serum IL-6, TNF-α, CPR and other inflamma-tory markers of patients with myocardial infarction effectively.