CAJ | 학술논문

梅毒这种慢性传染病，不仅临床表现复杂，而且病程长，危害性大，长期以来在临床中无法完整的培养好苍白密螺旋体，因而导致在临床中以苍白密螺旋体为基础的抗原研究受到了极大的阻碍。近些年来随着对苍白密螺旋体基因研究的不断深入，与苍白密螺旋体基因相关的抗原研究也得了极大的发展。目前临床中对于梅毒的诊断主要以血清学实验为主，掌握与其相关的血清学诊断方法，有利于梅毒的早发现、早治疗。本文将对苍白密螺旋体重组抗原以及与其对应的血清学诊断的进展做一个综述。
매독저충만성전염병，불부림상표현복잡，이차병정장，위해성대，장기이래재림상중무법완정적배양호창백밀라선체，인이도치재림상중이창백밀라선체위기출적항원연구수도료겁대적조애。근사년래수착대창백밀라선체기인연구적불단심입，여창백밀라선체기인상관적항원연구야득료겁대적발전。목전림상중대우매독적진단주요이혈청학실험위주，장악여기상관적혈청학진단방법，유리우매독적조발현、조치료。본문장대창백밀라선체중조항원이급여기대응적혈청학진단적진전주일개종술。
Syphilis,a chtonic infectious disease,with complicated clinical manifestaion,long course and huge perniciousness,and complete treponema pallidum(TP)is unable to culture in clinical for a long time,which leads hinders in the antigen study based on TP. In latest years,with the constant and deeper study on the TP genes,it reached a big process that the study on related antigens of TP genes. The diagnosis of sphilis is based on serology currently,so it would be helpful for the treatment of syphilis that mastering related serology diagnosis. This paper is a summary about the research progress on gene recombinant antigen of TP and its serology diagnosis.