CAJ | 학술논문

目的：对临床生化检验中改良终点法和原终点法的作用进行对比分析。方法临床对两种检验方法进行使用，对比分析改良终点法和原终点法之间的相关性以及线性浓度。结果在检测结果差异对比中，两种方法差异不明显，不具有统计学意义（P＞0.05）；改良终点在正常浓度下的批内CV和总CV测定要高于原终点法，在异常情况下低于原终点法，两者之间差异显著，具有统计学意义（P＜0.05）；改良终点法在高浓度测量下其线性浓度测定范围要大于原终点法，两者之间差异显著，具有统计学意义（P＜0.05）。结论在生化高浓度检验中，改良终点法应用优势明显高于原终点法，因此可以对改良终点法进行推广使用。
목적：대림상생화검험중개량종점법화원종점법적작용진행대비분석。방법림상대량충검험방법진행사용，대비분석개량종점법화원종점법지간적상관성이급선성농도。결과재검측결과차이대비중，량충방법차이불명현，불구유통계학의의（P＞0.05）；개량종점재정상농도하적비내CV화총CV측정요고우원종점법，재이상정황하저우원종점법，량자지간차이현저，구유통계학의의（P＜0.05）；개량종점법재고농도측량하기선성농도측정범위요대우원종점법，량자지간차이현저，구유통계학의의（P＜0.05）。결론재생화고농도검험중，개량종점법응용우세명현고우원종점법，인차가이대개량종점법진행추엄사용。
Objective To compare and analysis the effect of improved end-point method and the primary end point method in clinical biochemistry. Methods The two test methods were used,the correlation and linear concentration between the modified end-point method and the primary end point method were compared and analysised.Results The differences of detection result between the two groups were not significantly ,(P>0.05).Number of CV and total CV determination of the Improved terminal in the normal concentration were significantly higher than that of the primary end point method,and significantly lower than that of the primary end point method in exceptional circumstances,(P<0.05).Determination of the linear concentration range of the improved terminal methodin the high concentration measurement were significantly biger than that of the primary end point method,(P<0.05).Conclu-sion The advantage of improved endpoint method is higher than that of original endpoint method in the high concentration in the biochemical test, which can be used to improve the end-point method.