中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2014年
28期
25-27
,共3页
参芪扶正注射液%CRF%NSCLC
參芪扶正註射液%CRF%NSCLC
삼기부정주사액%CRF%NSCLC
Shenqi fuzheng injection%CRF%NSCLC
目的：探析参芪扶正注射液对晚期非小细胞肺癌（NSCLC）患者癌症相关疲劳（CRF）的干预效果。方法：选取2012年4月-2014年3月本院肿瘤治疗中心收治的97例晚期非小细胞肺癌患者，按照随机数字表法将其分为观察组49例和对照组48例，观察组给予参芪扶正注射液联合吉西他滨+顺铂（GP）方案治疗，对照组予以GP方案化疗。治疗2周期后，观察比较两组患者治疗前后癌症相关疲劳的情况、评价生活质量（QOL）及肿瘤近期疗效。结果：两组治疗后中重度疲劳阳性率均明显低于治疗前，且观察组治疗后中重度疲劳阳性率26.53%明显低于对照组的45.83%，生活质量改善有效率87.76%明显高于对照组的70.83%，客观缓解率53.10%明显高于对照组的33.33%，差异均有统计学意义（P<0.05）。结论：参芪扶正注射液联合GP方案化疗可有效减轻患者的癌症相关疲劳，提高患者的生活质量和肿瘤治疗有效率，值得临床推广。
目的：探析參芪扶正註射液對晚期非小細胞肺癌（NSCLC）患者癌癥相關疲勞（CRF）的榦預效果。方法：選取2012年4月-2014年3月本院腫瘤治療中心收治的97例晚期非小細胞肺癌患者，按照隨機數字錶法將其分為觀察組49例和對照組48例，觀察組給予參芪扶正註射液聯閤吉西他濱+順鉑（GP）方案治療，對照組予以GP方案化療。治療2週期後，觀察比較兩組患者治療前後癌癥相關疲勞的情況、評價生活質量（QOL）及腫瘤近期療效。結果：兩組治療後中重度疲勞暘性率均明顯低于治療前，且觀察組治療後中重度疲勞暘性率26.53%明顯低于對照組的45.83%，生活質量改善有效率87.76%明顯高于對照組的70.83%，客觀緩解率53.10%明顯高于對照組的33.33%，差異均有統計學意義（P<0.05）。結論：參芪扶正註射液聯閤GP方案化療可有效減輕患者的癌癥相關疲勞，提高患者的生活質量和腫瘤治療有效率，值得臨床推廣。
목적：탐석삼기부정주사액대만기비소세포폐암（NSCLC）환자암증상관피로（CRF）적간예효과。방법：선취2012년4월-2014년3월본원종류치료중심수치적97례만기비소세포폐암환자，안조수궤수자표법장기분위관찰조49례화대조조48례，관찰조급여삼기부정주사액연합길서타빈+순박（GP）방안치료，대조조여이GP방안화료。치료2주기후，관찰비교량조환자치료전후암증상관피로적정황、평개생활질량（QOL）급종류근기료효。결과：량조치료후중중도피로양성솔균명현저우치료전，차관찰조치료후중중도피로양성솔26.53%명현저우대조조적45.83%，생활질량개선유효솔87.76%명현고우대조조적70.83%，객관완해솔53.10%명현고우대조조적33.33%，차이균유통계학의의（P<0.05）。결론：삼기부정주사액연합GP방안화료가유효감경환자적암증상관피로，제고환자적생활질량화종류치료유효솔，치득림상추엄。
Objective:To explore the intervention effect of Shenqi Fuzheng injection on cancer-related fatigue (CRF)in the patients with non-small cell lung carcinoma(NSCLC)during chemotherapy.Method:97 patients with NSCLC in our tumor treatment center from April 2012 to March 2014 were selected,they were divided into the observation group for 49 cases and the control group for 48 cases according to the random number table method.The observation group was treated with GP chemotherapy combined with Shenqi Fuzheng injection and the control group was treated with GP chemotherapy.After 2 cycles of chemotherapy the CRF,cancer-related fatigue before and after treatment of the two groups were observed and compared,quality of life(QOL)and recent effect of tumor were evaluated.Result:The positive rate of moderate to severe fatigue of two groups after treatment were significantly lower than those of before treatment,and the positive rate of moderate to severe fatigue in observation group after treatment was 26.53%,it was significantly lower than 45.83%in control group,the QOL of observation group was 87.76%,it was significantly higher than 70.83%of control group,the objective response rate(RR)of observation group was 53.10%,it was significantly higher than 33.33%of control group,the differences were statistically significant(P<0.05).Conclusion:Shenqi Fuzheng injection combined GP chemotherapy can relieve the CRF and improve the QOL and short-term effect rate for NSCLC patients,is worthy of clinical promotion.
