中国当代医药
中國噹代醫藥
중국당대의약
PERSON
2014年
28期
89-90,93
,共3页
老年人%糖尿病%高血压%卡托普利%硝苯地平缓释片
老年人%糖尿病%高血壓%卡託普利%硝苯地平緩釋片
노년인%당뇨병%고혈압%잡탁보리%초분지평완석편
Elderly people%Diabetes mellitus%Hypertension%Captopril%Nifedipine sustained-release tablet
目的：研究卡托普利联合硝苯地平缓释片治疗老年糖尿病合并高血压的临床效果。方法回顾性分析2011年12月~2012年12月来本院就诊治疗的老年糖尿病合并高血压86例患者的临床资料，将患者随机分为观察组、对照组，每组各43例。观察组服用卡托普利12.5 mg，3次/d，联合硝苯地平缓释片20 mg，2次/d，口服，对照组只服用卡托普利12.5 mg，8周为1个疗程，比较两组的临床效果、收缩压(SBP)及舒张压(DBP)的变化情况。结果观察组的总有效率显著高于对照组，观察组治疗后的SBP、DBP较治疗前和对照组有显著变化(P<0.05)。结论 ACEI类药物联合CCB类药物治疗老年糖尿病合并高血压的临床效果显著优于单药，长期控制血压的能力以及服药依从性相对较强，值得临床推广。
目的：研究卡託普利聯閤硝苯地平緩釋片治療老年糖尿病閤併高血壓的臨床效果。方法迴顧性分析2011年12月~2012年12月來本院就診治療的老年糖尿病閤併高血壓86例患者的臨床資料，將患者隨機分為觀察組、對照組，每組各43例。觀察組服用卡託普利12.5 mg，3次/d，聯閤硝苯地平緩釋片20 mg，2次/d，口服，對照組隻服用卡託普利12.5 mg，8週為1箇療程，比較兩組的臨床效果、收縮壓(SBP)及舒張壓(DBP)的變化情況。結果觀察組的總有效率顯著高于對照組，觀察組治療後的SBP、DBP較治療前和對照組有顯著變化(P<0.05)。結論 ACEI類藥物聯閤CCB類藥物治療老年糖尿病閤併高血壓的臨床效果顯著優于單藥，長期控製血壓的能力以及服藥依從性相對較彊，值得臨床推廣。
목적：연구잡탁보리연합초분지평완석편치료노년당뇨병합병고혈압적림상효과。방법회고성분석2011년12월~2012년12월래본원취진치료적노년당뇨병합병고혈압86례환자적림상자료，장환자수궤분위관찰조、대조조，매조각43례。관찰조복용잡탁보리12.5 mg，3차/d，연합초분지평완석편20 mg，2차/d，구복，대조조지복용잡탁보리12.5 mg，8주위1개료정，비교량조적림상효과、수축압(SBP)급서장압(DBP)적변화정황。결과관찰조적총유효솔현저고우대조조，관찰조치료후적SBP、DBP교치료전화대조조유현저변화(P<0.05)。결론 ACEI류약물연합CCB류약물치료노년당뇨병합병고혈압적림상효과현저우우단약，장기공제혈압적능력이급복약의종성상대교강，치득림상추엄。
Objective To study the clinical effect of captopril combined with nifedipine sustained-release tablet in the treatment of elderly diabetes mellitus complicated with hypertension. Methods From December 2011 to December 2012, clinical data of 86 patients with elderly diabetes mellitus complicated with hypertension visited our hospital for treatment were selected and retrospectively analyzed.They were randomly and evenly divided into the observation group and control group.In the observation group,12.5 mg captopril (thrice a day) and 20 mg nifedipine sustained-release tablet (twice a day) were orally administered,while in the control group,only 12.5 mg captopril was provided.The course of treatment lasted 8 weeks.The clinical curative effect,change of systolic blood pressure (SBP) and diastolic blood pres-sure (DBP) were compared in both groups. Results The total effective rate in the observation group was obviously high-er than that in the control group,SBP,DBP in the observation group had significant change after treatment compared with those before treatment and the control group (P<0.05). Conclusion The clinical effect of angiotensin-converting enzyme inhibitors (ACEI) combined with calcium channel blockers (CCB) on treating elderly diabetes mellitus compli-cated with hypertension is remarkably superior to that by single drug with stronger long-term control of blood pressure and good compliance of taking drugs.It is worthy of expansion in clinic.
