中国当代医药
中國噹代醫藥
중국당대의약
PERSON
2014年
28期
71-72,75
,共3页
肝硬化%上消化道出血%奥曲肽%垂体后叶素
肝硬化%上消化道齣血%奧麯肽%垂體後葉素
간경화%상소화도출혈%오곡태%수체후협소
Cirrhosis%Upper digestive tract hemorrhage%Octreotide%Pituitrin
目的：比较奥曲肽与垂体后叶素治疗肝硬化并发上消化道出血的临床效果。方法将本院2011年5月~2013年12月收治的76例肝硬化并发上消化道出血患者分成治疗组39例和对照组37例。对照组给予常规治疗加垂体后叶素治疗，治疗组给予常规治疗联合奥曲肽治疗，连续使用7d，比较两组的临床疗效和不良反应。结果治疗组的总有效率为94.9%，对照组为64.9%，两组比较，差异有统计学意义(P<0.01)。治疗组出现呕吐2例、腹痛2例，不良反应发生率为10.2%，对照组出现呕吐3例，恶心1例，腹痛4例，高血压4例，头痛2例，不良反应发生率为37.8%，两组比较，差异有统计学意义(P=0.005)。结论奥曲肽治疗肝硬化并发上消化道出血的临床效果优于垂体后叶素，不良反应少，可在临床推广。
目的：比較奧麯肽與垂體後葉素治療肝硬化併髮上消化道齣血的臨床效果。方法將本院2011年5月~2013年12月收治的76例肝硬化併髮上消化道齣血患者分成治療組39例和對照組37例。對照組給予常規治療加垂體後葉素治療，治療組給予常規治療聯閤奧麯肽治療，連續使用7d，比較兩組的臨床療效和不良反應。結果治療組的總有效率為94.9%，對照組為64.9%，兩組比較，差異有統計學意義(P<0.01)。治療組齣現嘔吐2例、腹痛2例，不良反應髮生率為10.2%，對照組齣現嘔吐3例，噁心1例，腹痛4例，高血壓4例，頭痛2例，不良反應髮生率為37.8%，兩組比較，差異有統計學意義(P=0.005)。結論奧麯肽治療肝硬化併髮上消化道齣血的臨床效果優于垂體後葉素，不良反應少，可在臨床推廣。
목적：비교오곡태여수체후협소치료간경화병발상소화도출혈적림상효과。방법장본원2011년5월~2013년12월수치적76례간경화병발상소화도출혈환자분성치료조39례화대조조37례。대조조급여상규치료가수체후협소치료，치료조급여상규치료연합오곡태치료，련속사용7d，비교량조적림상료효화불량반응。결과치료조적총유효솔위94.9%，대조조위64.9%，량조비교，차이유통계학의의(P<0.01)。치료조출현구토2례、복통2례，불량반응발생솔위10.2%，대조조출현구토3례，악심1례，복통4례，고혈압4례，두통2례，불량반응발생솔위37.8%，량조비교，차이유통계학의의(P=0.005)。결론오곡태치료간경화병발상소화도출혈적림상효과우우수체후협소，불량반응소，가재림상추엄。
Objective To compare the clinical effect of octreotide and pituitrin in treatment of liver cirrhosis compli-cated with upper digestive tract hemorrhage. Methods 76 patients with liver cirrhosis complicated with upper digestive tract hemorrhage treated in our hospital from May 2011 to December 2013 were divided into the treatment group (n=39) and control group (n=37).The control group was given conventional therapy plusing pituitrin,the treatment group was given conventional treatment combined with octreotide,drugs were used continuously for 7 days.Clinical curative effect and adverse reaction of the two groups were compared. Results The total effective rate of the treatment group was 94.9%,and it was 64.9% in the control group,and there was a statistical difference of the two groups (P<0.01).There were 2 cases with vomiting,2 cases with abdominal pain,the incidence rate of adverse reaction was 10.2%,and there were 3 cases with vomiting,1 case with nausea,4 cases with abdominal pain,2 cases with headache,4 cases with hyper-tension,the incidence rate of adverse reaction was 37.8%,and there was a statistical difference of the incidence rate of adverse reaction in the two groups (P=0.005). Conclusion The clinical effect of octreotide treating liver cirrhosis com-plicated with upper digestive tract hemorrhage is better than pituitrin with less adverse reaction,and it can be popular-ized in clinic.
