CAJ | 학술논문

目的：探讨血脂和肝功能指标与脂肪肝发生的关系。方法：2012年7月-2014年6月收治脂肪肝患者186例作为观察组，以同期进行健康查体的206例健康者作为对照组。比较两组患者的血脂及肝功能指标，总结血脂及肝功能指标与脂肪肝发生的关系。结果：血脂检查结果：观察组总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白(HDL-C)指标均显著高于对照组，低密度脂蛋白(LDL-C)显著低于对照组，差异有统计学意义(P＜0.05)；肝功能检查结果：观察组谷丙转氨酶(ALT)、谷草转氨酶(AST)、r-谷氨酰转移酶(GGT)指标均显著高于对照组，差异有统计学意义(P＜0.05)。结论：血脂和肝功能指标与脂肪肝的发生具有直接关系，脂肪肝患者具有明显的脂代谢紊乱及肝细胞病理损伤，临床可将血脂及肝功能检查用于脂肪肝的早期诊断。
목적：탐토혈지화간공능지표여지방간발생적관계。방법：2012년7월-2014년6월수치지방간환자186례작위관찰조，이동기진행건강사체적206례건강자작위대조조。비교량조환자적혈지급간공능지표，총결혈지급간공능지표여지방간발생적관계。결과：혈지검사결과：관찰조총담고순(TC)、감유삼지(TG)、고밀도지단백(HDL-C)지표균현저고우대조조，저밀도지단백(LDL-C)현저저우대조조，차이유통계학의의(P＜0.05)；간공능검사결과：관찰조곡병전안매(ALT)、곡초전안매(AST)、r-곡안선전이매(GGT)지표균현저고우대조조，차이유통계학의의(P＜0.05)。결론：혈지화간공능지표여지방간적발생구유직접관계，지방간환자구유명현적지대사문란급간세포병리손상，림상가장혈지급간공능검사용우지방간적조기진단。
Objective:To explore the relationships of blood lipid and liver function index with fatty liver occurrence.Methods:186 cases of fatty liver patients were selected from July 2012 to June 2014 as the observation group; 206 cases of healthy subjects from health physical examination in the same period of were as control group.The blood lipid and liver function index of patients in two groups were compared,and the relationships of blood lipid and liver function index with fatty liver occurrence were summarized.Results:Blood lipid test results indicated that the total cholesterol(TC),triglyceride(TG) and high density lipoprotein(HDL-C) indexes of the observation group were significantly higher than those of the control group;the low density lipoprotein(LDL-C) was significantly lower than that of the control group;the differences were statistically significant(P<0.05). The liver function test results indicated that the alanine aminotransferase(ALT),aspartate aminotransferase(AST),r-glutamyl transferase(GGT) of the observation group were significantly higher than these of the control group;the differences were statistically significant(P<0.05).Conclusion:The blood lipid and liver function index with fatty liver occurrence have direct relationship.Patients with fatty liver have obvious lipid metabolic disorder and liver cell pathological damage.Clinical can use blood lipid and liver function examination for early diagnosis of fatty liver.