CAJ | 학술논문

目的：研究免疫抑制宿主肺炎的病原学构成特点。方法回顾性研究北京朝阳医院2002年1月至2008年12月免疫抑制宿主肺炎患者的住院病历。根据基础疾病分为移植后组、血液肿瘤和实体肿瘤组以及风湿免疫病组,分别描述其一般临床资料和病原学特征。结果本研究收录免疫抑制肺炎患者共计221例,其中男性123例(55.66%),平均年龄(52.22±15.96)岁,住院天数(中位数)26.5 d,病死率为25.34%。其中已知病原体的感染102例(46.15%),依次为：细菌性肺炎29例(13.12%),细菌+真菌的混合感染26例(11.76%),肺孢子菌肺炎21例(9.50%),真菌性肺炎19例(8.60%)。结论本研究中免疫抑制宿主肺炎患者已知病原体的感染中,以细菌+真菌的混合感染和细菌性肺炎最多,真菌性肺炎和 PCP 也较常见。
목적：연구면역억제숙주폐염적병원학구성특점。방법회고성연구북경조양의원2002년1월지2008년12월면역억제숙주폐염환자적주원병력。근거기출질병분위이식후조、혈액종류화실체종류조이급풍습면역병조,분별묘술기일반림상자료화병원학특정。결과본연구수록면역억제폐염환자공계221례,기중남성123례(55.66%),평균년령(52.22±15.96)세,주원천수(중위수)26.5 d,병사솔위25.34%。기중이지병원체적감염102례(46.15%),의차위：세균성폐염29례(13.12%),세균+진균적혼합감염26례(11.76%),폐포자균폐염21례(9.50%),진균성폐염19례(8.60%)。결론본연구중면역억제숙주폐염환자이지병원체적감염중,이세균+진균적혼합감염화세균성폐염최다,진균성폐염화 PCP 야교상견。
Objective To study the etiology of pneumonia in immunocompromised host (ICH). Methods The data of patients with pneumonia in ICH from Jannury 2002 to December 2008 were retrospectively analyzed.Patients were divided into three groups based on the underling diseases:post-transplantation group,hematologic malignancies and solid tumor group,and rheumatological disease group.The clinical data and etiology were analyzed.Results 221 ICH patients [123 male (55.66%), (52.22 ± 1 5.96 ) years old] were included.Hospital stays were 26.5 days (median).The hospital mortality of the ICH pneumonia was 25.34%.Etiologic diagnosis was achieved in 46.1 5% (102/221 ) patients.Conclusions In this study,the most frequent etiologies were mixed etiology (bacteria and fungi),bacterial pneumonia,pneumocystis pneumonia,fungal pneumonia.