中国医药科学
中國醫藥科學
중국의약과학
CHINA MEDICINE AND PHARMACY
2014年
17期
40-42
,共3页
透明质酸钠凝胶%输卵管阻塞%不孕
透明質痠鈉凝膠%輸卵管阻塞%不孕
투명질산납응효%수란관조새%불잉
Sodium hyaluronate%Tubal obstruction%Infertility
目的：比较透明质酸钠凝胶与松解液在宫腹腔镜联合COOK导丝治疗输卵管阻塞性不孕患者的临床疗效。方法选择2011年10月～2013年10月输卵管阻塞不孕患者55例，分成治疗组28例和对照组27例。治疗组使用医用透明质酸钠凝胶30mL，对照组使用松解液30mL。比较两组术后宫内妊娠率、异位妊娠率及卵管通畅率。结果术后3个月两组阻塞情况比较，治疗组阻塞率为0，对照组为3.7%，差异有统计学意义（P＜0.05）。术后1年内两组患者妊娠情况比较，治疗组宫内妊娠率60.7%、异位妊娠率7.1%，对照组宫内妊娠率33.3%、异位妊娠率29.6%，差异有统计学意义（P＜0.05）；两组患者输卵管通畅情况比较，治疗组通畅率75.0%、通而不畅率14.3%，对照组通畅率44.4%、通而不畅率40.7%，差异有统计学意义（P＜0.05）。结论在宫腹腔镜联合COOK导丝治疗的基础上使用透明质酸钠凝胶能够有效减少手术损伤，预防术后粘连，提高患者宫内妊娠率，降低异位妊娠率。
目的：比較透明質痠鈉凝膠與鬆解液在宮腹腔鏡聯閤COOK導絲治療輸卵管阻塞性不孕患者的臨床療效。方法選擇2011年10月～2013年10月輸卵管阻塞不孕患者55例，分成治療組28例和對照組27例。治療組使用醫用透明質痠鈉凝膠30mL，對照組使用鬆解液30mL。比較兩組術後宮內妊娠率、異位妊娠率及卵管通暢率。結果術後3箇月兩組阻塞情況比較，治療組阻塞率為0，對照組為3.7%，差異有統計學意義（P＜0.05）。術後1年內兩組患者妊娠情況比較，治療組宮內妊娠率60.7%、異位妊娠率7.1%，對照組宮內妊娠率33.3%、異位妊娠率29.6%，差異有統計學意義（P＜0.05）；兩組患者輸卵管通暢情況比較，治療組通暢率75.0%、通而不暢率14.3%，對照組通暢率44.4%、通而不暢率40.7%，差異有統計學意義（P＜0.05）。結論在宮腹腔鏡聯閤COOK導絲治療的基礎上使用透明質痠鈉凝膠能夠有效減少手術損傷，預防術後粘連，提高患者宮內妊娠率，降低異位妊娠率。
목적：비교투명질산납응효여송해액재궁복강경연합COOK도사치료수란관조새성불잉환자적림상료효。방법선택2011년10월～2013년10월수란관조새불잉환자55례，분성치료조28례화대조조27례。치료조사용의용투명질산납응효30mL，대조조사용송해액30mL。비교량조술후궁내임신솔、이위임신솔급란관통창솔。결과술후3개월량조조새정황비교，치료조조새솔위0，대조조위3.7%，차이유통계학의의（P＜0.05）。술후1년내량조환자임신정황비교，치료조궁내임신솔60.7%、이위임신솔7.1%，대조조궁내임신솔33.3%、이위임신솔29.6%，차이유통계학의의（P＜0.05）；량조환자수란관통창정황비교，치료조통창솔75.0%、통이불창솔14.3%，대조조통창솔44.4%、통이불창솔40.7%，차이유통계학의의（P＜0.05）。결론재궁복강경연합COOK도사치료적기출상사용투명질산납응효능구유효감소수술손상，예방술후점련，제고환자궁내임신솔，강저이위임신솔。
Objective To compare the clinical efficacy of hyaluronic sodium gel and release liquid in patients treated for fallopian infertility by Laparoscopy combined clinical efficacy COOK guide wire plug.MethodsWe selected 55 cases of patients who were treated for tubal obstruction infertility in our hospital from October 2011 to October 2013,they were randomly divided into two groups ,the treatment group and control group, the treatment group has 28 cases ,and the control group has 27 cases . The treatment group used 30ml of sodium hyaluronate gel, and the control group used 30ml of release liquid. We compared the rate of postoperative intrauterine pregnancy, the rate of ectopic pregnancy and tubal patency. ResultsThe obstruction status of the two groups after three months was as follow, the blocking rate of the treatment group was zero. While 3.7% in the control group, there was a significant difference (P<0.05). The pregnancy rate of 1 year postoperative ,the rate of intrauterine pregnancy was 60.7% in the treatment group ,the rate of ectopic pregnancy was 7.1% , while the rate of intrauterine pregnancy was 33.3% in the control group , the rate of ectopic pregnancy 29.6% , there was a significant difference (P<0.05 ) ; the patency rate of the treatment group was 75.0% , the poor patency rate of 14.3%, while the rate was 44.4% and 40.7% in the control group respectively, there was a significant difference (P<0.05 ) . Conclusion Using of sodium hyaluronate gel based on laparoscopic treatment of joint COOK guide wire Palace can effectively reduce the surgical trauma, prevention the postoperative adhesions, improve the rate of intrauterine pregnancy, and reduced the rate of ectopic pregnancy.
