CAJ | 학술논문

目的：探讨高龄高血压患者双下肢动脉闭塞症（PAOD）的危险因素。方法入选2012年8月至2013年8月首都医科大学附属北京友谊医院老年病科高龄高血压患者121例，收集临床资料，进行下肢动脉超声以及动态血压监测。根据下肢动脉超声结果将其分为PAOD组（n＝49）和非PAOD组（n＝72）。用SPSS 16.0软件包进行独立样本t检验、相关性分析和logistic回归分析。结果高龄高血压患者PAOD发病率为40.5%。PAOD组年龄、冠心病发生率、血肌酐以及糖化血红蛋白（HbA1c）水平较非PAOD组患者明显升高（P＜0.05）。logistic回归表明年龄、冠心病、白昼平均收缩压（dDBP）、HbA1c是PAOD的独立危险因素。回归方程：PAOD＝-12.169＋0.131×年龄＋1.341×冠心病-0.069×dDBP＋HbA1c×0.692。结论高龄高血压患者PAOD的发生率显著高于普通人群。年龄、冠心病、dDBP、HbA1c是PAOD的独立危险因素。
목적：탐토고령고혈압환자쌍하지동맥폐새증（PAOD）적위험인소。방법입선2012년8월지2013년8월수도의과대학부속북경우의의원노년병과고령고혈압환자121례，수집림상자료，진행하지동맥초성이급동태혈압감측。근거하지동맥초성결과장기분위PAOD조（n＝49）화비PAOD조（n＝72）。용SPSS 16.0연건포진행독립양본t검험、상관성분석화logistic회귀분석。결과고령고혈압환자PAOD발병솔위40.5%。PAOD조년령、관심병발생솔、혈기항이급당화혈홍단백（HbA1c）수평교비PAOD조환자명현승고（P＜0.05）。logistic회귀표명년령、관심병、백주평균수축압（dDBP）、HbA1c시PAOD적독립위험인소。회귀방정：PAOD＝-12.169＋0.131×년령＋1.341×관심병-0.069×dDBP＋HbA1c×0.692。결론고령고혈압환자PAOD적발생솔현저고우보통인군。년령、관심병、dDBP、HbA1c시PAOD적독립위험인소。
ObjectiveTo determine the risk factors for peripheral arterial occlusive disease (PAOD) in the very old patients with hypertension.Methods Totally 121 very old hypertensive subjects with age over 80yearsand systolic blood pressure≥140mmHg admitted in our department from August 2012 to August 2013 were enrolled in this study. Their clinical data were collected. Lower extremity arteries ultrasonography and ambulatory 24-hour blood pressure monitoring were carried out. They were divided into PAOD group (n=49) and non-PAOD group (n=72) accordingtothe results of lower extremity artery ultrasonography. Independentsamplest-test, correlation analysis and logistic regression analysis were employed to analyze the risk factors. Results The morbidity of PAOD was 40.5% in the very old patients with hypertension. PAOD patients had significantly higher age, incidence of coronary heart disease (CHD), serumcreatinine and glycosylated hemoglobin A1c (HbA1c) level (P<0.05). Logistic regression analysis revealed thatage, CHD, averageday diastolic blood pressure (dDBP) andHbA1c were independent risk factors for PAOD (regression equation: PAOD=-12.169+0.131×age+1.341×CHD-0.069×dDBP+HbA1c×0.692). Conclusion The morbidity of PAOD is significantly higher in the very old patients with hypertension thaninordinary population. Age, CHD, dDBP and HbA1c are independent risk factors for PAOD.